Leukemia is a clonal disease caused by genetic-epigenetic aberrations and we investigated the profile of circulating 741 microRNAs (miRNA) in plasma of newly diagnosed acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), chronic myeloid leukemia (CML) patients compared to healthy individuals. MiRNAs are small non-coding RNA molecules and have cri...

B8amide is a large molecule based on a derivative of the BODIPY laser dye PM567. Both molecules exhibit highly stable radical ions and similar absorbance and photoluminescence spectra. For B8amide, the redox potentials are E° ) -1.40 and 0.96 V vs SCE for reduction and oxidation, respectively, and for PM567, they are E° ) -1.37 and 0.94 V vs SCE. The absorbance and fluorescence λmax are 526 and...

BACKGROUND BRM (Brahma homologue) is well known for its critical role in tumor suppression and cancer development. Genetic variations in the promoter region of BRM have been suggested to be associated with loss of BRM expression and lung cancer risk. To the authors' knowledge, no study on the role of BRM genetic polymorphisms in hepatocellular carcinoma (HCC) risk has been performed. METHODOL...

Here, we sequenced the genome of the influenza A/Finland/741 M/2014(H1N1) virus and found that the virus accumulated oseltamivir resistance mutation H275Y in its neuraminidase during propagation in cell culture. This indicates that propagation in cell culture modifies virus genomes. The instability of influenza genomes should be taken into consideration during drug-sensitivity studies.

122]. Abstraction [132]. accelerated [741]. Accelerating [725]. Access [109, 52, 85, 130, 115, 147, 56, 208, 305, 587, 370, 617, 389, 368, 233, 169, 335]. accessing [200]. Accounting [188]. Accuracy [473]. accurate [231, 394]. achieving [304]. ACM [220]. ACME [666]. across [183]. Active [180, 108, 74, 698, 387].