Verifiable secret sharing (VSS) is a fundamental cryptographic primitive, lying at the core of secure multi-party computation (MPC) and, as the distributed analogue of a commitment functionality, used in numerous applications. In this paper we focus on unconditionally secure VSS protocols with honest majority. In this setting it is typically assumed that parties are connected pairwise by authen...

Replacement of hydrogenwith fluorine within three pairs of structurally similar small molecule inhibitors of heat shock protein 90 (HSP90) resulted in differences in inhibition constants (Ki) in vitro as well as marked differences in rat intravenous pharmacokinetic profiles. The difference in pharmacokinetic profiles between lower and higher affinity inhibitors (LAIs and HAIs, respectively) was...

We consider the round complexity of a basic cryptographic task: verifiable secret sharing (VSS). This well-studied primitive provides a good “test case” for our understanding of round complexity in general; moreover, VSS is important in its own right as a central building block for, e.g., Byzantine agreement and secure multi-party computation. The round complexity of perfect VSS was settled by ...

The pharmacokinetics of N-nitrosodimethylamine was studied in patas monkeys following i.v. doses of 0.5, 1.0, and 5.0 mg/kg and a p.o. dose of 1.0 mg/kg, and in Swiss mice at i.v. doses of 1.0 and 2.0 mg/kg. In the patas monkey the pharmacokinetics was linear over the i.v. dose range studied. The mean clearance (Cl), steady-state volume of distribution (Vss), mean residence time, and eliminatio...

It has been reported that values of tissue–plasma ratios (Kp) and resulting volume of distribution at steady state (Vss) are substantially overpredicted for several highly lipophilic drugs. This effect was observed particularly with the published version of the tissuecomposition-based model, which used experimentally determined unbound fraction in plasma (fup) as input for drugs. The reasons fo...

INTRODUCTION Empirical examinations of the efficacy of community-based programs to increase and sustain physical activity among youth are lacking. This study describes changes in vigorous physical activity during a 3-year period among children aged 9 to 13 years (tweens) in Lexington, Kentucky, following introduction of the VERB Summer Scorecard (VSS) intervention. METHODS A community coaliti...

We revisit the following question: what is the optimal round complexity of verifiable secret sharing (VSS)? We focus here on the case of perfect VSS where the number of corrupted parties t satisfies t < n/3, with n the total number of parties. Work of Gennaro et al. (STOC 2001) and Fitzi et al. (TCC 2006) shows that, assuming a broadcast channel, 3 rounds are necessary and sufficient for effici...

Two variable step size (VSS) techniques are proposed for adaptive decorrelation filtering (ADF) to improve the performance of competing speech separation. The first VSS method applies gradient adaptive step-size (GAS) to increase ADF convergence rate. Under some simplifying assumptions, the GAS technique is generalized to allow the combination with additional VSS techniques for ADF algorithm. T...