In this correspondence, a solution is developed for the regularized total least squares (RTLS) estimate in linear inverse problems where the linear operator is nonconvolutional. Our approach is based on a Rayleigh quotient (RQ) formulation of the TLS problem, and we accomplish regularization by modifying the RQ function to enforce a smooth solution. A conjugate gradient algorithm is used to min...

I . Rates of oxygen consumption and carbon dioxide production were measured in pigs from birth to 3 days of age in an open-circuit system. 2. The mean respiratory quotient (RQ) during the first 6 h following birth was 0.95 in fasted pigs and 0.91 in pigs which were allowed to feed. 3. The RQ fell during the remainder of the first postnatal day to mean values close to 0.85, whether the pigs were...

BACKGROUND Estrogen receptors (ER) alpha and beta play an important role in breast cancer. Recently, systemic adjuvant endocrine therapy with selective estrogen receptor modulator (SERM) tamoxifen has been challenged by aromatase inhibitors. Compared to antiestrogens, third-generation aromatase inhibitors (anastrozole and letrozole) exhibit an improved efficacy and tolerability. MATERIALS AND...

This paper subjects the GB parametric account of variation in Slavic numeral systems put forward in Franks (1995) to critical scrutiny from the perspective of minimalism. It is argued that the true nature of the variation lies in the case contexts in which QPs (phrases in which GEN-Q is assigned) can occur in the different languages. It is further argued that this variation is best understood i...

Measurement of the energy expenditure in man is a key step in the calculation of the energy requirements that are needed for clinical nutritional assessment and body weight management. Obese diabetic patients suffer from variable metabolic abnormalities that are associated with insulin resistance. The respiratory quotient (RQ) is an important metabolic indicator. It is the ratio of carbon dioxi...

I . Rates of oxygen consumption and carbon dioxide production were measured in pigs from birth to 3 days of age in an open-circuit system. 2. The mean respiratory quotient (RQ) during the first 6 h following birth was 0.95 in fasted pigs and 0.91 in pigs which were allowed to feed. 3. The RQ fell during the remainder of the first postnatal day to mean values close to 0.85, whether the pigs were...

BACKGROUND AND OBJECTIVES The detection of PML-RARalpha by real-time polymerase chain reaction (RQ-PCR) is becoming an important tool for monitoring minimal residual disease (MRD) in patients with acute promyelocytic leukemia (APL). However, its clinical value remains to be determined. Our aim was to analyze any associations between the risk of relapse and RQ-PCR results in different phases of ...

Multiparameter flow cytometry (MFC) and allele-specific oligonucleotide real-time quantitative PCR (ASO RQ-PCR) are the two most sensitive methods to detect minimal residual disease (MRD) in multiple myeloma (MM). We compared these methods in 129 paired post-therapy samples from 22 unselected, consecutive MM patients in complete/near complete remission. Appropriate immunophenotypic and ASO RQ-P...

OBJECTIVE The association between energy metabolism and prognosis in polytrauma patients has not yet been defined. The aim of this study was to describe energy metabolism and analyze the prognostic value of respiratory quotient (RQ) and nonprotein respiratory quotient (npRQ) in fasting polytrauma patients (fPP) and polytrauma patients with nutritional support (nsPP). METHODS Twenty-two polytr...