نتایج جستجو برای: رویکرد in silico

تعداد نتایج: 17020617  

Journal: :Nature Biotechnology 2008

Journal: : 2022

هدف: پژوهش حاضر با هدف شناسایی و اولویت‌بندی پیشایندها پسایندهای سبک رهبری چابک استفاده از روش دلفی فازی صورت پذیرفت.طراحی/ روش‌شناسی/ رویکرد: این نوع پژوهش‌های آمیخته رویکرد کیفی کمی در پارادایم استقرایی است که نظر هدف، کاربردی لحاظ ماهیت روش، اکتشافی است. جامعه آماری شرکت‌های دانش‌بنیان استان لرستان هستند 30 نفر خبرگان آنها بر اساس اصل کفایت نظری نمونه‌گیری هدفمند انتخاب شده‌اند. ابزار گردآور...

Journal: :acta medica iranica 0
masoumeh mohebi farabi eye research center, farabi eye hospital, tehran university of medical sciences, tehran, iran. abolfazl akbari colorectal research center, iran university of medical sciences, tehran, iran. nahid babaei department of molecular cell biology and genetics, bushehr branch, islamic azad university, bushehr, iran. abdolrahim sadeghi department of biochemistry and genetics, molecular and medicine research center, arak university of medical sciences, arak, iran. mansour heidari department of molecular cell biology and genetics, bushehr branch, islamic azad university, bushehr, iran. and experimental medicine research center, tehran university of medical sciences, tehran, iran. and department of medical genetics, school of medicine, tehran university of medical sciences, tehran, iran.

autosomal dominant congenital cataract (adcc) is the most common form of inherited cataracts and accounts for one-third of congenital cataracts. heterozygous null mutations in the crystallin genes are the major cause of the adcc. this study aims to detect the mutational spectrum of four crystallin genes, cryba1/a3 , crybb1 , crybb2 and crygd in an iranian family. genomic dna was isolated from w...

Journal: :iranian journal of pharmaceutical research 0
baharak khoshkholgh-sima department of biology, science and research branch, islamic azad university, tehran, iran soroush sardari drug design and bioinformatics unit, medical biotechnology department, biotechnology research center, pasteur institute, #69, pasteur ave., tehran, 13164, iran. jalal izadi mobarakeh physiology and pharmacology department, pasteur institute of iran, #69, pasteur ave., tehran, 13164, iran ramezan ali khavari-nejad department of biology, science and research branch, islamic azad university, tehran, iran.

mycobacterium tuberculosis, the main cause of tuberculosis (tb), has still remained a global health crisis especially in developing countries. tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. recently, there has been an alarming rise of drug resistant in tb. in this regard, it is an unmet need...

Journal: :Nature Biotechnology 1999

Journal: :Journal of Chemical Theory and Computation 2021

Many important processes affecting the earth’s climate are determined by physical properties of seawater. In addition, desalination seawater is a significant source drinking water for human population living in coastal areas. Since governing these depend on molecular interactions among its components, deeper knowledge at level would contribute to better understanding phenomena. However, strong ...

Background and purpose: Different genera of enterobacteriaceae have important roles in gastrointestinal diseases such as diarrhea. Among these, Enterotoxigenic E. coli (ETEC), enterohemorrhagic E. coli (EHEC), and Shigella are three main bacteria which are transmitted via contaminated food and water. Vaccination is a good strategy to combat these pathogens. In the present study, a chimeric anti...

Journal: :Genome Biology 2001

Journal: : 2022

هدف: با توجه به نگرانی‌های اجتماعی موجود در سال‌های اخیر دلیل بحران‌های اقتصادی، اجتماعی، مالی و زیست‌محیطی ناشی از تحریم‌ها، خط‌مشی دولت‌ها برای افزایش تاب‌آوری سمت اقتصاد مقاومتی سوق پیدا کرده است. هدف این پژوهش طراحی تبیین مدل سیاست‌گذاری دولت الکترونیک رویکرد وزارت علوم است.طراحی/ روش‌شناسی/ رویکرد: تحقیق حاضر لحاظ کاربردی توسعه‌ای بوده تکنیک تحلیل تم حاصل مصاحبه مدیران عالی اساتید دانشگاه ...

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