Composition of requirements models in Software Product Line (SPL) development enables stakeholders to derive the requirements of target software products and, very important, to reason about them. Given the growing complexity of SPL development and the various stakeholders involved, their requirements are often specified from heterogeneous, partial views. However, existing requirements composit...

The SBP-box transcription factor SQUAMOSA PROMOTER BINDING PROTEIN-LIKE8 (SPL8) is required for proper development of sporogenic tissues in Arabidopsis thaliana. Here, we show that the semisterile phenotype of SPL8 loss-of-function mutants is due to partial functional redundancy with several other members of the Arabidopsis SPL gene family. In contrast with SPL8, the transcripts of these latter...

Vascular calcification (VC) is a critical complication in patients with chronic kidney disease (CKD). The effects of spironolactone (SPL), a mineralocorticoid receptor (MR) antagonist, on VC have not been fully investigated in CKD. The present in vivo study determined the protective effects of SPL on VC in CKD rats. Rats were divided into a control group and four groups of rats with adenine-ind...

The right hemispheric dominance in visuospatial attention in human brain has been well established. Converging evidence has documented that ventral posterior parietal cortex (PPC) plays an important role in visuospatial attention. The role of dorsal PPC subregions, especially the superior parietal lobule (SPL) in visuospatial attention is still controversial. In the current study, we used repet...

Sphingosine-1-phosphate (S1P) is a potent lipid signaling molecule that regulates pleiotropic biological functions including cell migration, survival, angiogenesis, immune cell trafficking, inflammation, and carcinogenesis. It acts as a ligand for a family of cell surface receptors. S1P concentrations are high in blood and lymph but low in tissues, especially the thymus and lymphoid organs. S1P...

A software product line (SPL) usually involves a shared set of core assets and a series of application products. To ensure consistency, the evolution of the core assets and all the application products should be coordinated and synchronized under a unified evolution process. Therefore, SPL evolution often involves cross-product propagation and synchronization besides application derivation base...

Nowadays the decision whether to work with Software Product Lines (SPL) or not becomes a binding requirement for the strategic planning of companies. Learning how to choose the ideal tools to test a SPL is beneficial for companies in this planning process. Even though the ascending number of available software engineering testing tools, SPL testing lacks specific tools capable of supporting the...

A Software Product Line (SPL) that aims to develop context aware applications leaves challenges inherent to the SPL-based development approach and the type of application being developed (contextaware). These challenges leave open issues, like those related to how the context influences should be described. In the literature, there are studies that support the development of traditional SPL by ...

UNLABELLED BACKGROUND Structured Product Labeling (SPL) is a document markup standard approved by Health Level Seven (HL7) and adopted by United States Food and Drug Administration (FDA) as a mechanism for exchanging drug product information. The SPL drug labels contain rich information about FDA approved clinical drugs. However, the lack of linkage to standard drug ontologies hinders their ...

SPL scoping is the activity for bounding Software Product Lines (SPL), gathering heterogeneous knowledge from diverse sources. For achieving an agreement among different stakeholders, a commonalty scope must be understood and committed to. However, this stakeholders with individual interests complex task. This paper reports experience of small Colombian software company, applying evaluating col...