We investigated the consequences of colistin use in backyard chicken farms in Vietnam by examining the prevalence of mcr-1 in fecal samples from chickens and humans. Detection of mcr-1-carrying bacteria in chicken samples was associated with colistin use and detection in human samples with exposure to mcr-1-positive chickens.

In accordance with Peer Review process for US EPA's Model Calibrati on Report (MCR) for the Housatonic River (dated December 2004), I am enclosing a document entitled Comments of the General Electric Company on the U.S. Environmental Protection Agency's Model Calibration: Modeling of PCB Contamination in the Housatonic River, which was prepared on GE's behalf by Quantit ative Environmental Anal...

The effects of macromomycin (MCR), a high molecular weight peptide antibiotic, on cell division, DNA synthesis and DNA fragmentation were examined in cultured mammalian tumor cells. When MCR was added to HeLa cell culture simultaneously with [3H]thymidine, inhibition of DNA synthesis was observed depending on the amount of the drug present, although the inhibition was partial even at a high con...

Main control room (MCR) is an important site of the nuclear power plant (NPP), and the environmental condition in MCR shall be benefit to operators performing their task effectively and comfortably. With the development of HFE (human factor engineering), there is more attention to environment design of MCR. the MCR environment designmainly include noise reduction, illumination, air condition, i...

Since our first identification of plasmid-mediated colistin resistance gene mcr-1 in 2015 (Liu et al., 2016), it has been described in human clinics, domestic animals, foods, and the environment worldwide (Schwarz & Johnson, 2016). Although it is still rare, the emergence of mcr-1 in wild animals is of great concern. We summarized two previous reports on mcr-1 in wild birds from Lithuania and A...

We describe a hospital-based outbreak caused by multidrug-resistant, Klebsiella pneumoniae carbapenemase 3-producing, mcr-1-positive K. pneumoniae sequence type 45 in Portugal. mcr-1 was located in an IncX4 plasmid. Our data highlight the urgent need for systematic surveillance of mcr-1 to support adequate therapeutic choices in the nosocomial setting.

In this paper, we propose a delayed multiple copy retransmission (D-MCR) scheme. By using Markovian analytic method we present the performance evaluation of the D-MCR scheme in correlated fading channels. Both effective throughput and number of retransmissions are derived. The analytic results show that the D-MCR scheme can improve the performance greatly, especially in slow fading channels.

The spread of mcr-1 in the United States remains poorly defined. mcr-1-producing Escherichia coli that also carried blaSHV-12 was detected in a hospitalized patient. No additional cases were identified during screening of 801 Gram-negative isolates. Genomic sequencing identified an IncX4 mcr-1- harboring plasmid and ST117 clonal background associated with avian pathogenic E coli.