The complexity of high-performance computing (HPC) workflows is an important issue in the provision HPC cloud services most national supercomputing centers. This problem especially critical because it affects resource scalability, management efficiency, and convenience use. To solve this problem, while exploiting advantage bare-metal-level high performance, container-based solutions have been d...

BACKGROUND AND PURPOSE Hypoxia preconditioning (HPC), rapid or delayed, has been reported to induce neuroprotection against subsequent severe stress. Because delta-opioid receptor (DOR) plays an important role in delayed HPC-induced neuroprotection against severe hypoxic injury, we asked whether DOR is also involved in the rapid HPC-induced neuroprotection. METHODS Cultured rat cortical neuro...

Autophagy disruption leads to neuronal damage in hypoxic-ischemic brain injury. Rab7, a member of the Rab GTPase superfamily, has a unique role in the regulation of autophagy. Hypoxic preconditioning (HPC) provides neuroprotection against transient global cerebral ischemia (tGCI). However, the underlying mechanisms remain poorly understood. Thus, the current study explored the potential molecul...

Intracranial hemangiopericytoma (HPC) is a rare brain tumor with aggressive biologic behavior associated with high recurrence rate and often with extracranial metastasis. The most common sites of extracranial metastasis of the intracranial HPC are the long bones, lung, liver and abdominal cavity in the order of frequencies. Extracranial metastases usually occur long after the initial diagnosis ...

This paper compares three most common job management systems and their workings with Sun HPC ClusterTools 3.1. Various aspects such as installation, customization, scheduling and resource control issues are discussed. The three chosen systems are: Load Sharing Facility (LSF), Portable Batch System (PBS) and COmputing in DIstributed Networked Environment (CODINE)/ Global Resource Director (GRD)....

Herein, hydroxypropyl-beta-cyclodextrin (HPβCD) inclusion complex (IC) of a hydrophobic drug, sulfisoxazole (SFS) was incorporated in hydroxypropyl cellulose (HPC) nanofibers (HPC/SFS/HPβCD-IC-NF) via electrospinning. SFS/HPβCD-IC was characterized by DSC to investigate the formation of inclusion complex and the stoichiometry of the complex was determined by Job's plot. Modeling studies were al...

Although enumeration of CD34+ cells in the peripheral blood (PB) on the day of apheresis predicts the quantity of those cells collected, the flow cytometric techniques used are complex and expensive, and several hours are required to obtain the result in the clinical practice setting. The Sysmex SE-9000 automated haematology analyzer provides an estimate of immature cells, called hematopoietic ...

BACKGROUND Underreporting of elder mistreatment by health professionals is a significant problem. PURPOSE To investigate differences in elder mistreatment reporting threshold between hospice/palliative care (HPC) professionals and Adult Protective Services (APS); explore factors for not reporting elder mistreatment. DESIGN Cross-sectional questionnaire. SETTING/PARTICIPANTS Four HPC teams...

OBJECTIVES Although haematopoietic stem cells (HSCs) migrate to injured gut, therapeutic success clinically remains poor. This has been partially attributed to limited local HSC recruitment following systemic injection. Identifying site specific adhesive mechanisms underpinning HSC-endothelial interactions may provide important information on how to enhance their recruitment and thus potentiall...

A recent trend in modern high performance computing (HPC) system architectures employs “lean” compute nodes running a lightweight operating system (OS). Certain parts of the OS as well as other system software services are moved to service nodes in order to increase performance and scalability. This paper examines the impact of this HPC system architecture trend on HPC “middleware” software sol...