Blood smears stained with Wright-Giemsa were obtained from 1 24 patients with pathologically confirmed cutaneous T cell lymphoma (CTCL). 70 patients with various other cutaneous disorders, and ten healthy adult volunteers. These were examined in a blinded fashion for atypical lymphocytes with cerebriform nuclei (CLs). which were characterized further according to cell diameter. CLs. compricing ...

Blood smears stained with Wright-Giemsa were obtained from 124 patients with pathologically confirmed cutaneous T cell lymphoma (CTCL), 70 patients with various other cutaneous disorders, and ten healthy adult volunteers. These were examined in a blinded fashion for atypical lymphocytes with cerebriform nuclei (CLs), which were characterized further according to cell diameter. CLs, comprising u...

PURPOSE To assess the effect of overnight wear of a contact lens-based sensor (CLS) for monitoring of 24-hr intraocular pressure (IOP) fluctuations on central corneal thickness (CCT). MATERIALS AND METHODS  Changes in the CCT, mid-peripheral corneal thickness and central corneal radius (CCR) during overnight CLS wear in 20 eligible patients with ocular hypertension or established glaucoma wer...

OBJECTIVES The Collaborative Life Skills (CLS) program is a school-home intervention for students with attention-deficit/hyperactivity disorder (ADHD) symptoms and impairment. CLS integrates school, parent, and student treatments followed by booster sessions during a maintenance period into the subsequent school year. The program is delivered by school-based mental health providers. Beneficial ...

IMPORTANCE This study evaluates a new device that has been proposed to continuously monitor intraocular pressure (IOP) over 24 hours. OBJECTIVE To evaluate 24-hour IOP rhythm reproducibility during repeated continuous 24-hour IOP monitoring with noncontact tonometry (NCT) and a contact lens sensor (CLS) in healthy participants. DESIGN, SETTING, AND PARTICIPANTS Cross-sectional study of 12 y...

BACKGROUND Anastomotic leakage following colorectal surgery still occurs all too frequently, and this complication is difficult to predict. A nonfunctional stoma may reduce the risk of clinically relevant leaks but is overtreatment for most patients. More accurate assessments of the risk of anastomotic leakage would be very helpful in tailoring treatment in colorectal surgery. Therefore, a Colo...

MALDI imaging mass spectrometry (MALDI-IMS) has been used successfully in mapping different lipids in tissue sections, yet existing protocols fail to detect the diverse species of mitochondria-unique cardiolipins (CLs) in the brain which are essential for cellular and mitochondrial physiology. We have developed methods enabling the imaging of individual CLs in brain tissue. This was achieved by...

Intraocular pressure, a major modifiable risk factor for glaucoma, has been shown to fluctuate throughout the day in patients with glaucoma. The detection and measurement of this fluctuation may help guide the clinical management of glaucomatous individuals. The Sensimed Triggerfish contact lens sensor (CLS), which has recently gained approval for marketing in the USA, is designed to detect int...