Hippocampal neurogenesis is important for certain forms of cognition, and failing neurogenesis has been implicated in neuropsychiatric diseases. The neurogenic capacity of hippocampal neural stem/progenitor cells (NSPCs) depends on a balance between quiescent and proliferative states. Here, we show that the rate of fatty acid oxidation (FAO) regulates the activity of NSPCs. Quiescent NSPCs show...

Obesity is associated with a decrement in the ability of skeletal muscle to oxidize lipid. The purpose of this investigation was to determine whether clinical interventions (weight loss, exercise training) could reverse the impairment in fatty acid oxidation (FAO) evident in extremely obese individuals. FAO was assessed by incubating skeletal muscle homogenates with [1-(14)C]palmitate and measu...

The objective of the performed investigations was to isolate pathogenic fungi from contaminated maize cobs, to assess the appearance of maize cob fusariosis and to determine grain contamination with deoxynivalenol in the cultivation of genetically modified maize containing a gene resistance against European corn borer (Ostrinia nubilalis Hbn) as well as selected non-modified cultivars. The plan...

سابقه و هدف: به ­دلیل توسعه رشد جمعیت انسان، نیاز انسان منابع ضروری افزایش یافته است. فعالیت‌های مربوط صنایع همچنین کشاورزی به­ طور گسترده‌ای زمین‌های را آلوده کرده ترکیبات نفتی فلزات سنگین هر دو از آلاینده‌های رایج موجود در خاک‌هایی هستند که با فاضلاب تصفیه نشده آبیاری شده‌اند سلامت محیط زیست خطر مواجه می‌کنند. آلودگی خاک می‌تواند سبب کاهش امکان زراعت، نهایت تولید غذا برای شود. جنوب شهر تهران ...

Hepatic fatty acid oxidation (FAO) has long been implicated in the control of eating. Nevertheless, direct evidence for a causal relationship between changes in hepatic FAO and changes in food intake is still missing. Here we tested whether increasing hepatic FAO via adenovirus-mediated expression of a mutated form of the key regulatory enzyme of mitochondrial FAO carnitine palmitoyltransferase...

Carnitine palmitoyl transferase 2 (CPT2) and very-long-chain Acyl-CoA dehydrogenase (VLCAD) deficiencies are among the most common inborn mitochondrial fatty acid β-oxidation (FAO) disorders. Despite advances in their clinical and molecular characterizations, few therapeutic approaches exist for these diseases. Resveratrol (RSV) is a natural polyphenol extensively studied for its potential heal...

Sections relevant to biotechnology applications in food safety: Coordination was done by Masami Takeuchi (Food Safety Officer, Nutrition and Consumer Protection Division). Significant contributions were made by Sridhar Dharmapuri, FAO consultant. Technical contributions from several FAO colleagues, including Maria de Lourdes Costarrica (Senior officer, Nutrition and Consumer Protection Division...

Angiographic techniques have been used for the quantification of mitral or aortic and rarely tricuspid regurgitation. Mitral or aortic regurgitant volume per beat and the regurgitation fraction (fao and fm, respectively) are obtained from the angiographic determination of total left ventricular stroke volume (TSV) and forward stroke volume (FSV) estimated by a different technique. Although this...