BACKGROUND The impact of transoral endoscopic CO(2) laser microsurgery (TLM) for the treatment of Tis, T1, and T2 glottic cancer on local disease control, survival, and laryngeal preservation was investigated. METHODS From October 1999 to February 2008, 48 patients with a previously untreated early laryngeal malignant tumor who had been treated with TLM were enrolled in this study. Overall su...

Concentration of a nonfluorescent solution was determined in a 100-nm scale channel using a differential interference contrast thermal lens microscope (DIC-TLM). The DIC-TLM detects a refractive index change induced by sample heating as phase contrast. Concentration measurement was first performed in a nanochannel which is 21 m wide and 500 nm deep. The limit of detection (LOD) was 2.4 M and th...

The transmission line method (TLM) is a very efficient method for dynamic modelling of flow in pipelines, and uses delay elements to represent wave propagation. In this paper an existing TLM model is investigated and shown to have some deficiencies. Some adjustments are proposed to avoid these deficiencies and enhance the transient and steady state accuracy. Very good agreement is obtained betw...

A three-dimensional transmission-line matrix (TLM) model was developed to simulate microwave-scanning microscopy. A TLM algorithm that allows the simulation of the scanning was developed. Numerical modeling was carried out for frequencies that are commonly used in microwave nondestructive testing (1GHz – 20GHz). Structures with local discontinuities in the electric permittivity are modeled nume...

The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract This paper explores the coupling of the Perfectly Matched Layer technique (PML) with the Thin Layer Method (TLM), the combination of which allows making highly efficient and accurate simulations of layered half-spaces of infinite depth subjected to arbitrary dynamic so...

BACKGROUND Treatment for local glottic cancer recurrences after primary transoral laser microsurgery (TLM) has not been standardized. METHODS In 33 consecutive cases of salvage TLM after laser surgery for early glottic carcinoma failed, we retrospectively considered the potential clinicopathological prognostic factors in univariate statistical setting. RESULTS Patient age <65 years and path...