نتایج جستجو برای: رادیوفرکانس 900 مگاهرتز

تعداد نتایج: 15352  

Journal: :Canadian Medical Association Journal 2005

Journal: :Cancer research 2010
Marc Payton Tammy L Bush Grace Chung Beth Ziegler Patrick Eden Patricia McElroy Sandra Ross Victor J Cee Holly L Deak Brian L Hodous Hanh Nho Nguyen Philip R Olivieri Karina Romero Laurie B Schenkel Annette Bak Mary Stanton Isabelle Dussault Vinod F Patel Stephanie Geuns-Meyer Robert Radinsky Richard L Kendall

In mammalian cells, the aurora kinases (aurora-A, -B, and -C) play essential roles in regulating cell division. The expression of aurora-A and -B is elevated in a variety of human cancers and is associated with high proliferation rates and poor prognosis, making them attractive targets for anticancer therapy. AMG 900 is an orally bioavailable, potent, and highly selective pan-aurora kinase inhi...

2007
Mike W. Peng Shujun Zhang Xinchun Li

Does CEO duality – the practice of one person serving both as a firm’s CEO and board chair – contribute to or inhibit firm performance? Agency theory suggests that CEO duality is bad for performance because it compromises the monitoring and control of the CEO. Stewardship theory, in contrast, argues that CEO duality may be good for performance due to the unity of command it presents. The empiri...

2013
Yihui Pan Tracy Yue Wang Michael S. Weisbach

This paper documents the existence of a CEO Investment Cycle, in which disinvestment decreases over CEO tenure while investment increases, leading to “cyclical” firm growth in assets as well as in employment. The CEO investment cycle is present for both firings and non-performance related CEO turnovers. Its magnitude is substantial: the estimated difference in investment rate between the first ...

2012
Dong Chen Yudan Zheng

We conduct the first systematic analysis of the effect of CEO tenure on risk-taking. We document an overall positive impact of CEO tenure on risk-taking. Our results suggest that this positive relation may not be explained by tenure proxying for power, experiences, or human capital investment. Instead, the results are consistent with the hypothesis that the declining career concerns associated ...

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