When considering the principles of a pain control strategy by patients, reliable administration of additional bolus doses is important for providing the adequate analgesia and improving patient satisfaction. We compared the efficacy of elastomeric patient-control module (PCM) with conventional PCM providing epidural analgesia postoperatively.A noninferiority comparison was used. Eighty-six pati...

Platelets release a soluble factor into blood and conditioned medium (PCM) that decreases vascular endothelial permeability. The objective of this study was to determine the signal-transduction pathway that elicits this decrease in permeability. Permeability-decreasing activity of PCM was assessed by the real-time measurement of electrical resistance across cell monolayers derived from bovine p...

Phase change materials (PCM) take advantage of latent heat that can be stored or released from a material over a narrow temperature range. PCM possesses the ability to change their state with a certain temperature range. These materials absorb energy during the heating process as phase change takes place and release energy to the environment in the phase change range during a reverse cooling pr...

Six approaches for downscaling climate model outputs for use in hydrologic simulation were evaluated, with particular emphasis on each method’s ability to produce precipitation and other variables used to drive a macroscale hydrology model applied at much higher spatial resolution than the climate model. Comparisons were made on the basis of a twenty-year retrospective (1975– 1995) climate simu...

The protein L-isoaspartyl-O-methyltransferase functions to initiate the repair of isomerized aspartyl and asparaginyl residues that spontaneously accumulate with age in a variety of organisms. Caenorhabditis elegans nematodes lacking the pcm-1 gene encoding this enzyme display a normal lifespan and phenotype under standard laboratory growth conditions. However, significant defects in developmen...

Phase-change memory (PCM) has emerged in recent years as the most promising technology for non-volatile memory due to its very high throughput performance and read/write endurance as well as future scalability. Multilevel functionality is crucial for increasing the capacity and thus enhancing the cost per GByte competitiveness of the PCM technology. However, storage of multiple resistance level...

A centrosome consists of two barrel-shaped centrioles embedded in a matrix of proteins known as the pericentriolar material (PCM). The PCM serves as a platform for protein complexes that regulate organelle trafficking, protein degradation and spindle assembly. Perhaps most important for cell division, the PCM concentrates tubulin and serves as the primary organizing centre for microtubules in m...

Phase-change memory (PCM) is a promising technology that is anticipated to be used in the memory hierarchy of future computer systems. However, its access time is relatively slower than DRAM and it has limited endurance cycle. Due to this reason, PCM is being considered as a high-speed storage medium (like swap device) or long-latency memory. In this paper, we adopt PCM as a virtual memory swap...

BACKGROUND The centrosome is composed of a centriole pair and pericentriolar material (PCM). By marking the site of PCM assembly, the centrioles define the number of centrosomes present in the cell. The PCM, in turn, is responsible for the microtubule (MT) nucleation activity of centrosomes. Therefore, in order to assemble a functional bipolar mitotic spindle, a cell needs to control both centr...