There have been major advances reported over the past decade in previously untreated chronic lymphocytic leukemia (CLL) with chemo-immunotherapy approaches now the treatment of choice.2 A decade ago, chlorambucil was the treatment of choice. However, CLL is a disease of the elderly with a median age at diagnosis of 72 years, and almost 70% of CLL patients are older than 65 years at the time of ...

Participants at a community health information network in Glens Falls, N.Y., have come face-to-face with obstacles that could have meant the end to this rural health network that the New York Department of Health and the John A. Hartford Foundation helped launch more than two years ago. Instead, John Laliberte, Glens Falls Hospital's director of information systems, and the rest of the IS team ...

Prior research on child poverty has focused heavily on the roles of family structure and, to a lesser extent, parental work patterns to explain trends over time and differences across groups. However, immigrant child poverty has increased significantly over the past three decades even though labor force participation is high among immigrants and immigrant families are likely to be headed by a m...

The reproductive system is controlled by gonadotropin releasing hormone (GnRH) secretion from the brain, which is finely modulated by a number of factors including gonadal sex steroids. GnRH cells do not express estrogen receptor α, but feedback is transmitted by neurons that are at least 'one step back' from the GnRH cells. Modulation by season, stress and nutrition are effected by neuronal pa...

This paper discusses specific techniques for rehabilitation of chronic low back pain through aggressive physical therapy with behavioral support. The rationale for approaching the outcome dimensions of impairments in back function and pain-related disability as opposed to chronic pain symptoms is explained. This approach requires that impairments in back function are systematically identified t...