objective(s):  medicinal benefits of quantum dots have been proved in recent years but there is little known about their toxicity especially in vivo toxicity. in order to use quantum dots in medical applications, studies ontheir in vivo toxicity is important.  materials and methods:cdse:zns quantum dots were injected in 10, 20, and 40 mg/kg doses to male mice10 days later, mice were sacrificed ...

staphylococcus aureus is an opportunistic pathogen and remains a common cause of burn wound infections. different studies have shown that entrapment of plant-derived compounds into liposomes could increase their anti-staphylococcus aureus activity. silymarin is the bioactive extract from the known plant silybum marianum l. the objective of this study was to evaluate efficacy of silymarin in fre...

background: we evaluated the effect of the ethanolic extract of scrophularia striata on the iranian strain of leishmania major (mrho/ir/75/er) both in vitro and in vivo conditions methods: the effective dose (ed) of ethanolic extract of s. striata were determined using  mtt assay  on the growth of promastigote forms of  l. major in axenic culture media. then, the ed 50 of  s. striata on mice pe...

introduction: urine morphine test, in several countries is the most primarily available qualitative test for detecting opioid abusers. since the users of illicit drugs attempt to defeat urine tests and there are also plenty of claims that usage of hd (high dose) contraceptive pills can result in false-negative results, we decided to design the present study to investigate the probable in vitro ...

the objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (ir) and modified release (mr) tablets. the experiment included rats with both normoglyceamia and streptozocin (stz)-induced hyperglyceamia. several mr formulations were designed and in vitro drug release profile was assessed by a dissolution test. for the fur...