Superior androgen receptor (AR) function in subjects carrying a GGN repeat length of 23 (GGN23) has been indicated in vivo. Therefore, the activity of the AR carrying GGN23 combined with CAG22 was compared to the AR with GGN10, 24 and 27, respectively, in the presence of 0.1-100 nM testosterone or DHT. At 100 nM DHT, GGN24 showed 35% lower transactivating activity (95% [CI]: 20-50%) than GGN23....

This research aims to evaluate the achievement of rural development in study area after UNESCO designated Toba Caldera Geopark as a member Global Network (GGN) July 2020. For that purpose, authors conduct measure relationship geotourism with area. The methods employed are library research, discussion, observation, field trips and questionnaires 127 respondents from village government officers, ...

OBJECTIVES This work was a comparative study that aimed to find a proper method for accurately segmenting persistent ground glass nodules (GGN) in thin-section computed tomography (CT) images after detecting them. METHODS To do this, we first applied five types of semi-automatic segmentation methods (i.e., level-set-based active contour model, localized region-based active contour model, seed...

Genes encoding hormone receptors are among candidate genes modulating the risk of ovarian cancer. We aimed to assess a frequency of PGRG+331A, FSHRAla307Thr, and FSHRSer680Asn polymorphic variants, and the length of (CAG)n and (GGN)n repeat tracts in the androgen receptor gene (AR) with respect to ovarian cancer risk and outcome. We genotyped 215 ovarian cancer patients and 352 unaffected contr...

PURPOSE To compare manual measurements of diameter, volume, and mass of pulmonary ground-glass nodules (GGNs) to establish which method is best for identifying malignant GGNs by determining change across time. MATERIALS AND METHODS In this ethics committee-approved retrospective study, baseline and follow-up CT examinations of 52 GGNs detected in a lung cancer screening trial were included, r...

In this letter, we investigate the performance of reconfigurable intelligent surface (RIS)-assisted communications, under assumption generalized Gaussian noise (GGN), over Rayleigh fading channels. Specifically, consider an RIS, equipped with $N$ </inl...

Abstract Optimization problems that include regularization functions in their objectives are regularly solved many applications. When one seeks second-order methods for such problems, it may be desirable to exploit specific properties of some these when accounting curvature information the solution steps speed up convergence. In this paper, we propose SCORE (self-concordant regularization) fram...

The gravitational coupling of nearby massive bodies to test masses in a wave (GW) detector cannot be shielded, and gives rise 'gravity gradient noise' (GGN) the detector. In this paper we show that for any GW using local Inner Solar System, GGN from motion field $\sim 10^5$ System asteroids presents an irreducible noise floor detection rises exponentially at low frequencies. This severely limit...