OBJECTIVES Preventing postoperative recurrence after ileocolonic resection (ICR) for Crohn's disease (CD) is challenging. Defining the disturbances of the microbial composition and community structure after ICR and their link with early disease recurrence is crucial. DESIGN Microbiota composition (fingerprinting and 16S rDNA sequencing) and community structure (correlation networks of bacteri...

Ion current rectification (ICR), defined as an increase in ion conduction at a given polarity and a decrease in ion conduction for the same voltage at the opposite polarity, i.e., a deviation from a linear ohmic response, occurs in conical shaped pores due to the voltage dependent solution conductivity within the aperture. The degree to which the ionic current rectifies is a function of the siz...

Abstract BACKGROUND: Intermittent calorie restriction (iCR) reduces inflammation in preclinical models and people with Multiple Sclerosis (pwMS). Mechanisms could be related to changes levels of adipose tissue-derived adipokines reduced systemic gut microbiota composition. AIMS: Evaluate the effects iCR on levels, metabolic immune/inflammatory biomarkers compared a control unrestricted diet (Ct...

The paper aims at verifying the influence of supplemented spirulina on the form of erythrocytes and the content of hemoglobin of anaemic ICR male rats that have done exercises. The method adopted: scanning electronic microscope and full automated hematology analyzer are used to studying the influence of supplementing spirulina on the form of erythrocytes and the content of hemoglobin of rats. R...

BACKGROUND Invasive cervical resorption (ICR) is not well understood by the professional, being misdiagnosed, leading to inappropriate treatment and unnecessary loss of tooth. INTRODUCTION ICR is defined as a localized process of resorption, which begins in the cervical area of the tooth, just below the epithelial junction and above the ridge crest in the area of the connective tissue inserti...

OBJECTIVE The aim of this study was to better delineate the complex interrelationship among insulin resistance (IR), secretion rate (ISR), and clearance rate (ICR) to increase plasma insulin concentrations in obesity. METHODS Healthy volunteers (92 nondiabetic individuals) had an insulin suppression test to measure IR and graded-glucose infusion test to measure ISR and ICR. Obesity was define...

High mass measurement accuracy of peptides in enzymatic digests is critical for confident protein identification and characterization in proteomics research. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) can provide low or sub-ppm mass accuracy and ultrahigh resolving power. While for ESI-FT-ICR-MS, the mass accuracy is generally 1 ppm or better, with matrix-assisted l...

OBJECTIVE EEG recording is useful for neurological and cognitive assessment, but acquiring reliable data in infants and special populations has the challenges of limited recording time, high-amplitude background activity, and movement-related artifacts. This study objectively evaluated our previously proposed ERP analysis techniques. METHODS We compared three artifact removal techniques: Conv...

Objective. Effect of isopropanolic Cimicifuga racemosa extract (iCR) on uterine fibroid size compared with tibolone. Method. The randomized, double-blind, controlled study in China enrolled 244 patients aged 40-60 years with menopausal symptoms (Kupperman Menopause Index ≥ 15). The participants were treated with either iCR of 40 mg crude drug/day (N = 122) or tibolone 2.5 mg/day (N = 122) orall...

Abstract Background Endoscopic post-operative recurrence (ePOR) is common following ileocecal resection (ICR) in patients with Crohn’s disease (CD), reaching up to, 70% at, 1-year. In clinical trials, prophylaxis anti-TNF therapies demonstrated a decrease ePOR to around, 20% Here we aimed compare the effectiveness of vedolizumab (VDZ) and ustekinumab (UST) anti-TNFs for preventing after curativ...