Nonsteroidal anti-inflammatory drugs have been shown to reduce the incidence of gastrointestinal cancers, but the propensity of these drugs to cause ulcers and bleeding limits their use. H2S has been shown to be a powerful cytoprotective and anti-inflammatory substance in the digestive system. This study explored the possibility that a H2S-releasing nonsteroidal anti-inflammatory drug (ATB-346)...

To compare the differences in access to a minimally invasive surgery (MIS) for gender-neutral (appendectomy) vs. gender-specific (hysterectomy) operation rapidly growing biologically female population at Veterans Health Administration (VHA). This is retrospective cohort study of biological veterans Affairs Surgical Quality Improvement Project (VASQIP) database who underwent appendectomy or hyst...

CrystEngComm This journal is © The Royal Society of Chemistry 2014 Department of Chemistry & Biochemistry and Materials Science Institute, University of Oregon, Eugene, Oregon 97403-1253, USA. E-mail: [email protected], [email protected]; Fax: +1 541 346 0487; Tel: +1 541 346 0456, +1 541 346 1695 † Electronic supplementary information (ESI) available: Experimental details, spectroscopic data and...

BACKGROUND Non-steroidal antiinflammatory drugs (NSAIDs) are the most commonly prescribed agents for arthritic patients, although gastric effects limit their long-term use. Considering the reported gastric safety of hydrogen sulfide (H2S)-releasing NSAIDs, in addition to the anti-inflammatory effects of H2S administration to rats with synovitis, we decided to evaluate the effects of the H2S-rel...