Paraoxonase 1 (PON1) activity is consistently predictive of vascular disease, although the genotype at four functional PON1 polymorphisms is not. To address this inconsistency, we investigated the role of all common PON1 genetic variability, as measured by tagging single-nucleotide polymorphisms (tagSNPs), in predicting PON1 activity for phenylacetate hydrolysis, LDL susceptibility to oxidation...

This paper is about single three-point perspective historical photography-based CAAD modeling (amateur camera calibration, pose and 3-d reconstruction) of man-made environments, buildings and monuments, rich in geometrical regularity. The proposed method, gains profit from the presence in the image (historical photography) of three vanishing directions and two orthogonal object edges with known...

This paper introduces a new perspective of transforming the use of Computer Aided Architectural Design (CAAD) in designing the built environment. This perspective conceives the design process of the built environment to be an integration of technical and social processes. Virtual Design Environments (VDEs) open exciting new territory and have the potential to advantage the design of the built e...

The subject of this paper is the research that aims at efficiency improvement of acquisition of 3D building models from digital images for Computer Aided Architectural Design (CAAD). The results do not only apply to CAAD, but to all applications where polyhedral objects are involved. The research is concentrated on the integration of a priori geometric object information in the modeling process...

In the paper-based world, CAAD-associations, such as SIGRADI, and scientific publishers aim at getting the right people together and for making sure their work gets distributed to their peers. Electronic networks, such as the Internet, are providing scientists with the means to pursue those activities on their own. In this paper we present the goals of an EU project called SciX (Scientific info...

Improvements and new developments in the fields of sensor and computer technology have had a major impact on photogrammetry. Nowadays a variety of cameras and photogrammetric systems is available. The application of a S-VHS camcorder together with a system for Digital Photogrammetry and Architectural Design in architectural photogrammetry is demonstrated on a practical object. The imaging syste...

Tomorrow’s architectural practitioners seemingly need to gain an overview of, if not master, a wide range of computer aided architectural design applications, from image making to Building Information Modelling (BIM) to digital fabrication. However, we are sceptical whether there is wide recognition that there is value in a broader appreciation of the underlying principles that organize these a...

XThe issue of collaborative design has been elaborated extensively within the framework of previous CAAD–conferences. Today, an appreciation for traditional attitudes and methods can be observed, but interestingly, a mixture of approaches is also noticeable (computational techniques used in low–tech fabrication environments, for example). This allows for a round–table survey of the current stat...