Adenoviruses are common pathogens, mostly targeting ocular, gastrointestinal and respiratory cells, but in some cases infection disseminates, presenting in severe clinical outcomes. Upon dissemination and contact with blood, coagulation factor X (FX) interacts directly with the adenovirus type 5 (Ad5) hexon. FX can act as a bridge to bind heparan sulphate proteoglycans, leading to substantial A...

Let (X,Y ) be a random point in R with a (joint) cumulative distribution function (c.d.f.) F and continuous marginal c.d.f.’s FX and FY , so that F (x, y) = P(X 6 x, Y 6 y), FX(x) = P(X 6 x), and FY (y) = P(Y 6 y) for all real x and y. Then F is continuous as well, since |F (x2, y2)−F (x1, y1)| 6 |FX(x2)−FX(x1)|+|FY (y2)−FY (y1)| for all x1, y1, x2, y2 in R. Vice versa, if F (x, y) is continuou...

One of the most critical issues that developers face in developing automatic systems or software agents for electronic markers is that of endowing the agents with appropriate trading strategies. In this paper, we examine the problem in the Foreign Exchange (FX) market and we use an agent-based FX market simulation to examine which trading strategies lead to market states in which the stylized f...

Lifestyle-related problems are becoming a major health threat in East Asian countries. Therefore, finding an efficacious nutraceutical for this population is important. One candidate is fucoxanthin (Fx), a carotenoid abundantly found in edible brown seaweed that has been associated with a number of valuable health-promoting benefits. Unfortunately, clinical studies of Fx are limited. In the pre...

Cholesterol ester-rich (CER) VLDL accumulate rapidly in the plasma of rabbits fed cholesterol-enriched diets. However, the major loci of enhanced synthesis of subfractions of CER-VLDL, their interaction with macrophages, and their relative contribution to atherogenesis have not yet been elucidated. To determine whether anabolism is hepatic or intestinal, subfractions of CER-VLDL were characteri...

The mechanism for how fucoxanthin (FX) suppressed adipose accumulation is unclear. We aim to investigate the effects of FX on metabolic rate and expressions of genes related to thermogenesis, mitochondria biogenesis and homeostasis. Using a 2 × 2 factorial design, four groups of mice were respectively fed a high sucrose (50% sucrose) or a high-fat diet (23% butter + 7% soybean oil) supplemented...