Apart from cigarette smoking, genetic factors seem to be of importance in the development of lung cancer. The present case-control study investigated frequencies of five inflammatory response gene polymorphisms (TNF-alpha-308, TNF-beta-Intron1-252, IL-6-174, IL-10-819 and IL-10-1082) in patients with lung cancer and controls. The study population consisted of 117 patients with lung cancer (77 p...

Juvenile idiopathic arthritis (JIA) is the most common cause of chronic childhood disability and encompasses a number of disease subgroups. In this study we have focused on systemic JIA (sJIA), which accounts for approximately 11% of UK JIA cases. This study reports the investigation of three members of the IL10 gene family as candidate susceptibility loci in children with sJIA. DNA from 473 un...

BACKGROUND Single nucleotide polymorphisms (SNP) in the promoter region of the interleukin (IL)-10 genes have a role in determining hepatitis B virus (HBV) outcome. OBJECTIVES This study evaluates the correlation between HBV infection and SNP in IL-10 gene promoter. PATIENTS AND METHODS Ninety-six HBV-infected patients (32 chronic hepatitis B infection patients, 34 healthy carriers, 30 spon...

PURPOSE To identify occult pneumothorax with oblique chest X-ray (OCXR) in clinically suspected patients. METHODS In this retrospective study, we examined 1082 adult multitrauma patients who were admitted to our emergency service between January 2016 and January 2017. Clinical findings that suggest occult pneumothorax were rib fracture, flail chest, chest pain, subcutaneous emphysema, abrasio...

Background: Hepatitis B Virus (HBV) is a universal health challenge all around the world. Several factors like viral load, genetic characteristics, age, sex, and immune status contribute to variable clinical outcomes of HBV infection. The sequels infection vary remarkably among persons ranging from spontaneous deletion persistent Objective: present study aimed evaluate association single nucleo...

We have obtained optical spectra of seven stars in the old galactic cluster M 67 that are unusual sources of X-rays, and investigate whether the X-ray emission is due to magnetic activity or to mass transfer. The two binaries below the giant branch S 1063 and S 1113, the giant with the white dwarf companion S 1040 and the eccentric binary on the subgiant branch S 1242 show magnetic activity in ...