نتایج جستجو برای: اپی گالو کاتچین گالات egcg

تعداد نتایج: 4032  

2012
Yoshimi Matsumoto Kunihiro Kaihatsu Kunihiko Nishino Miho Ogawa Nobuo Kato Akihito Yamaguchi

(-)-Epigallocatechin-3-O-gallate (EGCG) has useful antiviral, antimicrobial, antitoxin, and antitumor properties. Previously, Mori et al. (2008) found that addition of long acyl chains (C16-18) to EGCG enhanced its anti-influenza virus activity up to 44-fold. The chemical stability of EGCG against oxidative degradation was also enhanced by acylation. We further evaluated the in vitro activity s...

2013
Vladislav Snitsarev Michael N. Young Ross M. S. Miller David P. Rotella

(-)-Epigallocatechin 3-O-gallate (EGCG) a molecule found in green tea and known for a plethora of bioactive properties is an inhibitor of heat shock protein 90 (HSP90), a protein of interest as a target for cancer and neuroprotection. Determination of the spectral properties of EGCG fluorescence in environments similar to those of binding sites found in proteins provides an important tool to di...

Journal: :Acta Biomaterialia 2021

In tissue engineering, excessively generated reactive oxygen species (ROS) during biomaterial implantation or cell transplantation is a one of major causes diminishing therapeutic effects. this study, we prepared surfaces coated with antioxidant epigallocatechin gallate (EGCG) and metal ions, evaluated their anti-oxidative ROS scavenging properties. We revealed that EGCG-coating on polycaprolac...

ژورنال: پژوهش های جانوری 2015

این پروژه با هدف بررسی اثرات ضد باکتریایی کاتچین، فرولیک اسید و عصاره دانه انگور بر بالکتری های عامل مسمومیت غذایی در میگوی پرورشی انجام شد. این پروزه در چهار تیمار و سه تکرار انجام شد. تیمارها شامل میگوی عمل آوری شده با غلظت های 1/0 درصد کاتچین، 3 % فرولیک اسید و 1 درصد عصاره دانه انگور به مدت 15 دقیقه و میگوی شاهد هستند. تیمارها به مدت 6 ماه در سردخانه 18- درجه سلسیوس نگهداری شدند. کیفیت نمون...

2014
Hae-Suk Kim Michael J. Quon Jeong-a Kim

Green tea is rich in polyphenol flavonoids including catechins. Epigallocatechin 3-gallate (EGCG) is the most abundant and potent green tea catechin. EGCG has been extensively studied for its beneficial health effects as a nutriceutical agent. Based upon its chemical structure, EGCG is often classified as an antioxidant. However, treatment of cells with EGCG results in production of hydrogen pe...

2013
Adam J. Smith Padmini Kavuru Kapildev K. Arora Sheshanka Kesani Jun Tan Michael J. Zaworotko R. Douglas Shytle

The most abundant polyphenol in green tea, epigallocatechin-3-gallate (EGCg), has recently received considerable attention due to the discovery of numerous health-promoting bioactivities. Despite reports of its poor oral bioavailability, EGCg has been included in many dietary supplement formulations. Conventional preformulation methods have been employed to improve the bioavailability of EGCg. ...

2015
Bo Zhang Bing Wang Shuhua Cao Yongqiang Wang

Traumatic brain injury (TBI) is a major cause of mortality and long-term disability, which can decrease quality of life. In spite of numerous studies suggesting that Epigallocatechin-3-gallate (EGCG) has been used as a therapeutic agent for a broad range of disorders, the effect of EGCG on TBI remains unknown. In this study, a weight drop model was established to evaluate the therapeutic potent...

2014
Chunjian Zhao Shuaihua Liu Chunying Li Lei Yang Yuangang Zu

In this study, epigallocatechin gallate (EGCG) palmitate was synthesized and its anti-porcine reproductive and respiratory syndrome virus (PRRSV) activity was studied. Specifically, EGCG palmitate was evaluated for its ability to inhibit PRRSV infection in MARC-145 cells when administered as pre-, post-, or co-treatment. EGCG and ribavirin were used as controls. The results showed that a 50% cy...

2017
Steven Elder John Clune Jaylyn Walker Paul Gloth

As a non-crosslinked osteochondral xenograft would be mechanically inferior to native cartilage and vulnerable to premature degradation, we seek a safe and effective method of xenograft stabilization. The purpose of this study was to evaluate the capacity for epigallocatechin gallate (EGCG) to stabilize a decellularized porcine osteochondral xenograft through collagen crosslinking. Our objectiv...

Journal: :American journal of physiology. Cell physiology 2009
Hui-Chen Ku Hsin-Huei Chang Hsien-Chun Liu Chiao-Hsin Hsiao Meng-Jung Lee Yu-Jung Hu Pei-Fang Hung Chi-Wei Liu Yung-Hsi Kao

Insulin and (-)-epigallocatechin gallate (EGCG) have been reported to regulate fat cell mitogenesis and adipogenesis, respectively. This study investigated the pathways involved in EGCG modulation of insulin-stimulated mitogenesis in 3T3-L1 preadipocytes. EGCG inhibited insulin stimulation of preadipocyte proliferation in a dose- and time-dependent manner. EGCG also suppressed insulin-stimulate...

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