the variants of angiotensin converting enzyme (ace) and matrix metalloproteinases (mmps) genes might be involved in the pathogenesis of end stage renal disease (esrd) and hypertension. we studied the ace insertion/deletion (i/d) and mmp-7 a-181g variants in 99 unrelated esrd patients and 117 individuals without renal complications from western iran with kurdish ethnic background. the frequency ...

cladribine, an analogue of deoxyadenosine, is highly toxic for both non-dividing and proliferating cells and has shown activity in the treatment of several malignancies. therefore, the aim of the present study is to investigate the cytotoxicity effect of cladribine (2-cda) on the breast cancer cell line, mcf-7 (estrogen receptor positive, er+). mtt assay, annexin v-fluorescein/pi and hoechst 33...

a series of fe3o4 supported on mesoporous fdu-12 silica systems were prepared by the hydrothermal conditions. the surface properties of the functionalized catalyst were analyzed by a series of characterization techniques like ftir, xrd, n2 adsorption–desorption and tem. xrd and adsorption–desorption analysis shows that the mesostructure of fdu silica remains intact after fe3o4 modifications, wh...

a facile and efficient method for the preparation of 1, 1-diacetates of aldehydes is improved.p2o5/sio2 catalyzed 1, 1-diacetates formation from aldehydes in dry media. advantages of this methodare the use of an inexpensive and selective catalyst with high yields in simple operation and shortreaction time under solvent-free conditions.

background: the pathogenesis of gestational trophoblastic disease (gtd) is not clearly known. objective: in this study, immunoexpression of proteins bcl-2 and beclin-1 in trophoblastic lesions and normal trophoblastic tissue was conducted to study the mechanism of apoptotic and autophagic cell death that is expected to complete the study of gtd pathogenesis. materials and methods: bcl-2 and bec...