Purpose Inspite of the attention resilience receives in relation to public policy and management, very few studies have analysed internal mechanics sector organisations see what is producing their resilience. Considering management control systems (MCSs) as drivers organisational change, this paper aims explore role determinants sector. The attempts open black box functioning focusing on one co...

Motion capture is gaining significance in educational research. Different motion systems (MCSs) are used research for different purposes and ways, which creates a diversity that difficult to monitor. The aim of this article provide an overview MCSs their uses addressing primary secondary school education. We conducted systematic review focusing on the types concrete being used, looking at how t...

A key feature of many eukaryotic cells, most prominently seen in developing neurons, is their ability to form and extend membrane protrusions. How protrusion formation is linked to exocytic membrane trafficking is largely unclear. In a recent paper published in Nature, Raiborg et al identify a crucial role in this process for dynamic membrane contact sites (MCSs) between the ER and endosomes. T...

Let’s look at an example. For s = 〈1,−5, 2,−1, 3〉, we know that 〈1〉, 〈2,−1, 3〉, and 〈−5, 2〉 are all contiguous subsequences of s—whereas 〈1, 2, 3〉 is not. Among such subsequences, we’re interested in finding one that maximizes the sum. In this particular example, we can check that mcss(s) = 4, achieved by taking the subsequence 〈2,−1, 3〉. We have to be careful about what our MCSS problem return...

Membrane contact sites (MCSs) function to facilitate the formation of membrane domains composed of specialized lipids, proteins, and nucleic acids. In cells, membrane domains regulate membrane dynamics and biochemical and signaling pathways. We and others identified a highly conserved family of sterol transport proteins (Ltc/Lam) localized at diverse MCSs. In this study, we describe data indica...

ABSTRACT Membrane contact sites (MCSs) between the endoplasmic reticulum (ER) and late endosomes/lysosomes (LE/lys) are emerging as critical hubs for diverse cellular events, changes in their extents linked to severe neurological diseases. While recent studies show that synaptotagmin-like mitochondrial-lipid-binding (SMP) domain-containing protein PDZD8 may mediate formation of ER–LE/lys MCSs, ...

Regions of close apposition between two organelles, often referred to as membrane contact sites (MCSs), mostly form between the endoplasmic reticulum and a second organelle, although contacts between mitochondria and other organelles have also begun to be characterized. Although these contact sites have been noted since cells first began to be visualized with electron microscopy, the functions ...

A key feature of many eukaryotic cells, most prominently seen in developing neurons, is their ability to form and extend membrane protrusions. How protrusion formation is linked to exocytic membrane trafficking is largely unclear. In a recent paper published in Nature, Raiborg et al identify a crucial role in this process for dynamic membrane contact sites (MCSs) between the ER and endosomes. T...

NV junctions (nucleus-vacuole junctions) in Saccharomyces cerevisiae are MCSs (membrane contact sites) formed through specific interactions between Vac8p on the vacuole membrane and Nvj1p in the outer nuclear membrane, which is continuous with the perinuclear ER (endoplasmic reticulum). NV junctions mediate a unique autophagic process that degrades portions of the yeast nucleus through a proces...

Abstract. Deep convection possesses markedly distinct properties at different spatiotemporal scales. We present an original high-resolution (4 km, hourly) unified data product of mesoscale convective systems (MCSs) and isolated deep (IDC) in the United States east Rocky Mountains examine their climatological characteristics from 2004 to 2017. The is produced by applying updated Flexible Object ...