Allylestrenol (ALE) and chlormadinone acetate (CMA) were administered to patients with prostatomegaly by the double-blind method, and the effects of these antiandrogens on their sexual function were objectively compared. Each agent was orally administered to 58 patients in a dosage of 50 mg/day for 12 consecutive weeks. For the objective evaluation of the sexual function, nocturnal penil tumesc...

Staphylococcus capitis EPK1 produces a glycylglycine endopeptidase, ALE-1 (M. Sugai, T. Fujiwara, T. Akiyama, M. Ohara, H. Komatsuzawa, S. Inoue, and H. Suginaka, J. Bacteriol. 179:1193-1202, 1997), which hydrolyzes interpeptide pentaglycine chains of cell wall peptidoglycan of S. aureus. Characterizations of the enzyme activity and cloning of ale-1 revealed that ALE-1 is very similar to prolys...

BACKGROUND Reliable blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) phenotypic biomarkers of Alzheimer's disease (AD) or mild cognitive impairment (MCI) are likely to emerge only from a systematic, quantitative, and aggregate examination of the functional neuroimaging research literature. METHODS A series of random-effects activation likelihood estimation (ALE...

The leaves of Artemisia argyi Lev. et Vant. and A. princeps Pamp. are well known medicinal herbs used to treat patients in China, Japan, and Korea with skin problems such as eczema and itching, as well as abdominal pain and dysmenorrhoea. We investigated the anti-inflammatory effects of Artemisia leaf extract (ALE) using CD mice and Raw 264.7 cells. The effects of ALE on histopathological chang...

The West Indian manatee (Trichechus manatus latirostris) has become an endangered species partly because of an increase in the number of collisions with boats. A device to alert boaters of the presence of manatees is desired. Previous research has shown that background noise limits the manatee vocalization detection range (which is critical for practical implementation). By improving the signal...

We describe a modular HPSG implementation , based on a set of tools rather than a single monolithic engine such as ALE. With these tools we can use techniques for much faster compiling and parsing than ALE. We use two-stage grammar compilation with partial execution and a concurrent process implementation of the chart for fast parsing. We compile HPSG lexical rules into Prolog rules used at run...

In this paper, we study the change of the ADM mass of an ALE space along the Ricci flow. Thus we first show that the ALE property is preserved under the Ricci flow. Then, we show that the mass is invariant under the flow in dimension three (similar results hold in higher dimension with more assumptions). A consequence of this result is the following. Let (M, g) be an ALE manifold of dimension n...

BACKGROUND Hypercholesterolaemia is directly associated with an increased risk for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf extract (ALE) has been implicated in lowering cholesterol levels. Whether ALE is truly effective for this indication is still a matter of debate. This is an update of a review first published in 2002 and last updated in 2009. OBJECTIVE...

Droplet impact onto a solid surface is modeled and numerically simulated using an ALE formulation of the Navier-Stokes free surface equations. The triple line dynamics aspect is modeled implicitely through the Shikhmurzaev theory. Those equations involve a generalized Navier slip boundary conditions with the variation of the surface tension near the triple line (thus a local Marangoni effect). ...