background: increasing the complexity in modern radiotherapy techniques have increased the delivery time lowering consequently the treatment efficacy. through simulating the delivery time delay encountered in such techniques, its’ effect on two cancer cell lines and the compensating doses given to prevent such effect was investigated. materials and methods: f10b16 and 4t1 cancer cell lines were...

The primary purpose of this chapter is to provide public health officials, toxicologists, and other interested individuals and groups with an overall perspective of the health physics and toxicology of ionizing radiation. It contains descriptions and evaluations of radiological and toxicological studies and epidemiologic investigations and provides conclusions, where possible, on the relevance ...

Radiation is any kind of energy transmitted without an intermediate medium. Radiant generally wave-shaped, most commonly sinusoidal. There are two types radiation: ionizing radiation and non-ionizing radiation. Ionizing that causes the process ejecting electrons from atoms to form ion pairs. Attention should be paid radiation, particularly its sources, types, properties, effects, methods avoida...

Fractionated, high-dose total body irradiation (TBI) is used therapeutically to myeloablate and immune suppress patients undergoing hematopoietic stem cell (HSC) transplantation. Acute exposure to ionizing radiation can have fatal effects on the hematopoietic and immune systems. Currently, therapies aimed at ameliorating ionizing radiation-associated toxicities are limited. In the February 2014...

background: although ionizing radiation is widely used to diagnose many diseases, the relevant hazards are known to be as an important limitation of its application. it is believed that the awareness of ionizing radiation dose values is one of the main stages in patient's radiation protection. the purpose of this study has been to investigate the level of physicians' knowledge about r...

radio-protectors are agents that protect human cells and tissues from undesirable effects of ionizing radiation by mainly scavenging radiation-induced free radicals. although chemical radio-protectors diminish these deleterious side effects they induce a number of unwanted effects on humans such as blood pressure modifications, vomiting, nausea, and both local and generalized cutaneous reaction...

Exposure to ionizing radiation has potential for acute and chronic health effects. Within the general public of the United States, there may be a discrepancy between perceived and actual health risks. In conjunction with the Vermont Department of Health, a survey designed to assess public perception and knowledge of ionizing radiation was administered at 6 Vermont locations (n = 169). Descripti...

We previously reported that methoxyamine (an inhibitor of base excision repair) potentiates iododeoxyuridine (IUdR)-induced radiosensitization in human tumor cells. In this study, we investigated the potential mechanisms of this enhanced cell death. Human colorectal carcinoma RKO cells were exposed to IUdR (3 micromol/L) and/or methoxyamine (3 mmol/L) for 48 hours before ionizing radiation (5 G...

Nuclear medicine uses ionizing radiation for both in vivo diagnosis and therapy. Ionizing radiation comes from a variety of sources, including x-rays, beam therapy, brachytherapy, and various injected radionuclides. Although PET and SPECT remain clinical mainstays, optical readouts of ionizing radiation offer numerous benefits and complement these standard techniques. Furthermore, for ionizing ...

Knowing the amount of ionizing photons from young star-forming galaxies is of particular importance to understanding the reionization process. Here we report initial results of Subaru/Suprime-Cam deep imaging observation with a special narrow-band filter to optimally trace ionizing radiation from galaxies at z > 3. The unique wide field-of-view of Suprime-Cam enabled us to search for ionizing p...