Cell migration during wound healing requires adhesion receptor turnover to enable the formation and disassembly of cell-extracellular matrix contacts. Although recent advances have improved our understanding of integrin trafficking pathways, it is not known how extracellular ligand engagement controls receptor dynamics. Using atomic force microscopy, we have measured cell avidity for fibronecti...

objective: objective: dermal papilla and hair epithelial stem cells regulate hair formation and growth cycle. damage to or losing of these cells can cause hair loss. although several studies have claimed to reconstitute hairs using rodent cells in animal model, a stable human hair follicle reconstitution protocol needs more studies. here in this study we evaluated hair induction through injecti...

BACKGROUND Migraine headache is a primary neurologic disease affecting millions of people worldwide. As a consequence, quality of life is diminished, productivity suffers (through loss of work force), and treatment costs are substantial. The occurrence rate in the general population is quite high, with women accounting for 3 of every 4 cases. METHODS Between January 2011 and May 2012, a total...

background: this study examined the effects of dry needling on chronic heel pain due to plantar fasciitis.   methods: during this single-blinded clinical trial, 20 eligible patients were randomized into two groups: a case group treated with dry needling and a control group. patients' plantar pain severity, (using modified visual analog scale [vas] scoring system), range of motion of ankle joint...

background: human hair can be used as an inexpensive and accessible adsorbent to remove a variety of pollutants from air. although several studies have been done on removal of formaldehyde from wastewater by human hair, to date no study has investigated using hair to remove formaldehyde from air. therefore, the aim of this study was to remove formaldehyde from synthetic contaminated air by a re...

The original strain of proopiomelanocortin (POMC)-deficient mice (Pomc-/-) was generated by homologous recombination in 129X1/SvJ (A(w)/A(w))-derived embryonic stem cells using a targeting construct that deleted exon 3, encoding all the known functional POMC-derived peptides including alpha MSH, from the Pomc gene. Although these Pomc-/- mice exhibited adrenal hypoplasia and obesity similar to ...

Pheomelanin is synthesized within melanocytes of hair follicles in mice of appropriate Agouti (a)or Extension (e)locus genic constitution. Alleles at the a-locus program pheomelanogenesis by altering the internal environment of hair follicles whereas alleles at the e locus do so by direct action through the genome of the melanocyte. For example, although transplanted recessive yellow (ele) mela...

purpose: the purpose of this study was to investigate the effect of kinesio-taping on the range of motion of cervical lateral flexion point in subjects with trigger point in upper trapezius muscle. methods: a total of 32 subjects with myofascial trigger point in upper trapezius participated in this randomized controlled trial (rct). the subjects were randomly assigned to two groups: kinesio-tap...