OBJECTIVE To evaluate orthopedic metal artifact reduction algorithm (O-MAR) in CT orthopedic metal artifact reduction at different tube voltages, identify an appropriate low tube voltage for clinical practice, and investigate its clinical application. MATERIALS AND METHODS The institutional ethical committee approved all the animal procedures. A stainless-steel plate and four screws were impl...

CONSUELO PLATA,1 DAVID B. MOUNT,2 VERENA RUBIO,1 STEVEN C. HEBERT,2 AND GERARDO GAMBA1 1Molecular Physiology Unit, Department of Nephrology and Mineral Metabolism, Instituto Nacional de la Nutrición Salvador Zubirán and Department of Medicine, Instituto de Investigaciones Biomédicas, National University of Mexico, Mexico City CP 14000, Mexico; and 2Division of Nephrology, Department of Medicine...

Carroll, Robert E., Kristina A. Matkowskyj, Subrata Chakrabarti, Thomas J. McDonald, and Richard V. Benya. Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G655– G665, 1999.—Epithelial cells lining the adult human colon do not normally express gastrin-releasing peptide (GRP) o...

Lutz, Peter L., and Liscia Manuel. Maintenance of adenosine A1 receptor function during long-term anoxia in the turtle brain. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R633–R636, 1999.—It has been established that adenosine has a critical role in the extraordinary ability of the turtle brain to survive anoxia. To further investigate this phenomenon we compared rat and turt...

Doughty, Joanne M., Frances Plane, and Philip D. Langton. Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1107–H1112, 1999.—In rat mesenteric artery, endothelium-derived hyperpolarizing factor (EDHF) is blocked by a combination of apamin and charybdotoxin (ChTX). The site of action of these t...

Oyekan, A. O., K. McAward, J. Conetta, L. Rosenfeld, and John C. McGiff. Endothelin-1 and CYP450 arachidonate metabolites interact to promote tissue injury in DOCAsalt hypertension. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R766–R775, 1999.—Inhibition of cytochrome P-450 (CYP450) enzymes with cobalt chloride (CoCl2) prevented hypertension, organ hypertrophy, and renal inju...

Khan, Janine Y., Rosario A. Rajakumar, Robert A. McKnight, Uday P. Devaskar, and Sherin U. Devaskar. Developmental regulation of genes mediating murine brain glucose uptake. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R892–R900, 1999.—We examined the molecular mechanisms that mediate the developmental increase in murine whole brain 2-deoxyglucose uptake. Northern and Western...

Asfaha, Samuel, Cameron J. Bell, John L. Wallace, and Wallace K. MacNaughton. Prolonged colonic epithelial hyporesponsiveness after colitis: role of inducible nitric oxide synthase. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G703–G710, 1999.—Colonic epithelial secretion is an important host defense mechanism. We examined whether a bout of colitis would produce long-lasting changes i...

Kleine, Teri J., Gerald J. Gleich, and Simon A. Lewis. Eosinophil peroxidase increases membrane permeability in mammalian urinary bladder epithelium. Am. J. Physiol. 276 (Cell Physiol. 45): C638–C647, 1999.—Eosinophil peroxidase (EPO), a cationic protein found in eosinophils, has been reported to be cytotoxic independent of its peroxidase activity. This study investigated with electrophysiologi...

MARK O. BEVENSEE,1 ESTHER BASHI,1 WOLF-RÜDIGER SCHLUE,2 GREGORY BOYARSKY,3 AND WALTER F. BORON1 1Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520; 2Institut für Neurobiologie, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany; and 3Department of Physiology and Biophysics, University of Texas Medical Branch, Galvesto...