new derivatives of 2-[2-(2-chlorophenoxy)phenyl]-1,3,4-oxadiazole as candidates for agonistic effect on benzodiazepine receptors were synthesized. conformational analysis and superimposition of energy minima conformers of the novel compounds on estazolam, a known benzodiazepine agonist, revealed that the main proposed benzodiazepine pharmacophores were well matched. in pharmacological evaluatio...

In this paper, we proposed a new, highly scalable method to solve the database selection problem when the number of local databases in a metasearch engine is very large. For single-term queries, this method guarantees all desired documents to be retrieved. Experiments were conducted to show that this method is very eeective for typical short Internet queries. We also illustrated that the our da...

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the density and viscosity values at t= (293.15 to 323.15) k for binary mixtures of nitromethane with 2-propanol, 2-butanol and 2-pentanol were measured over the entire composition range. from the experimental data, excess molar volumes, thermal expansion coefficients, excess thermal expansions, partial molar volumes at infinite dilution and deviations in viscosity were calculated. the results w...