OBJECTIVE(S) Based on knowledge from traditional herbal medicine, Ferula assa-foetida (asafoetida) has several therapeutic applications but there is less knowledge about its effect on neurons. MATERIALS AND METHODS In order to evaluate neuronal differentiation, neuronal like cells were stained against neuronal specific markers β-Tubulin III and MAP2. After establishment of neuronal differenti...

Background and objectives: Ferula assa-foetida (asafoetida) is a native Iranian species which grows in different regions and climates in Iran. The plant is well known in Iranian Traditional Medicine as well as folk medicine for treatment of diseases. Several studies have been carried out on the essential oil of this species collected from different are...

In this experiment, the chemical composition of the essential oils obtained from Ferula assa-foetida oleo-gum resin collected from two different sites of Yazd province (Tabas and Yazd) in the center of Iran, were identified. The gas chromatography mass-spectroscopy (GC/MS) data showed that the qualitative composition of the components appeared to be constant in two different regions. Moreover, ...

Several complications attributed with Herpes virus related infections and the emergence of drug resistant viruses prompt scientists to search for new drugs. Several terpenoids and coumarins have shown anti HSV effects while no sesquiterpene coumarins have been previously tested for HSV treatment. Three sesquiterpene coumarins badrakemin acetate (1), kellerin (2) and samarcandin diastereomer (3)...

Background: Dicrocoeliasis and fascioliasis are foodborne parasitic diseases of the biliary tract, resulting from Dicrocoelium dendriticum Fasciola hepatica causing extensive financial losses serious health problems in ruminants. Due to low-performance medications, drug delivery is a tremendous project improve interventions available for these diseases. Objectives: This study aimed determine an...