نتایج جستجو برای: кb
تعداد نتایج: 140 فیلتر نتایج به سال:
Abstract Diabetes mellitus (DM) is a set of metabolic diseases defined by persistently high blood sugar level. Mesenchymal stem cells (MSCs) are novel potential therapeutic intervention in treatments various diseases, which also referred to as regenerative medicine. We aimed compare the pro-inflammatory cytokines’ levels during bone marrow mesenchymal (BM-MSCs) transplantation rats with induced...
Galectin-1 has previously been shown to be strongly expressed in activated pancreatic stellate cells (PSCs) and promote the development and metastasis of pancreatic ductal adenocarcinoma (PDAC). However, the molecular mechanisms by which Galectin-1 promotes the malignant behavior of pancreatic cancer cells remain unclear. In this study, we examined the effects of Galectin-1 knockdown or overexp...
Activation of TLR signaling through recognition of pathogen-associated molecular patterns is essential for the innate immune response against bacterial and viral infections. We have shown that p120-catenin (p120) suppresses TLR4-mediated NF-кB signaling in LPS-challenged endothelial cells. In this article, we report that p120 differentially regulates LPS/TLR4 signaling in mouse bone marrow-deri...
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