extended-spectrum β-lactamase (esbl)-producing enterobacteria has become a considerable global concern because of their potential dissemination in humans, in domestic animals, wildlife and the environment. the present study aimed to explore the esbl producing  enterobacteria in aquatic sources of bangladesh as the water may be the potential source of dissemination of this alarming antimicrobial...

conclusions beside our study, the detection of mbl genes were reported in a few studies conducted in iran. the spread of detected mbls producing p. aeruginosa were unprecedented in the region due to the lack of independent related researches or the novel incidence of these genes. this detection must be noted by associated clinical and health care services. results from 240 p. aeruginosa isolate...

OBJECTIVES AmpC β-lactamases are classified as Amber Class C and Bush Group 1. AmpC β-lactamases can hydrolyze broad and extended-spectrum cephalosporins, and are not inhibited by β-lactamase inhibitors such as clavulanic acid. This study was conducted to identify DHA-23, a novel plasmid-mediated and inducible AmpC β-lactamase obtained from Enterobacteriaceae. METHODS A total of 210 carbapene...

β-Lactamases inactivate β-lactam antibiotics by hydrolysis of their endocyclic β-lactam bond and are a major cause of antibiotic resistance in pathogenic bacteria. The zinc dependent metallo-β-lactamase enzymes are of particular concern since they are located on highly transmissible plasmids and have a broad spectrum of activity against almost all β-lactam antibiotics. We present here essential...

conclusions our study showed that the prevalence of esbl-producing k. pneumoniae at king khalid hospital was significantly high. routine detection of esbl-producing microorganisms is required by each of the laboratory standard detection methods to control the spread of these infections and allow a proper therapeutic strategy. for detection, the phenotypic confirmatory disc diffusion test is sim...

The production of β-lactamase enzymes is the main mechanism of resistance to β-lactam antibiotics in gramnegative bacilli. Therefore, it is important to identify the β-lactamases-producing bacteria for the treatment of caused infections. This article aimed to review the recent literature and guidelines regarding phenotypic detection of β-lactamases in common gram-negative bacilli in clinical sa...

Background: Enterococci faecalis are predominating species of Enterococci causing nosocomial infections. Acquisition of resistance to antibacterial agents, and ability to transfer the resistant genes made them clinically important. This study was performed to determine the frequency of isolation of different species of Enterococci, and the antibacterial resistance pattern of the isolated specie...

In this study, 78 isolates of Escherichia coli isolated from Korean beef cattle farms were investigated for the production of extended-spectrum β-lactamase (ESBL) and/or AmpC β-lactamase. In the disc diffusion test with ampicillin, amoxicillin, cephalothin, ceftiofur, cefotaxime, ceftazidime, and cefoxitin, 38.5% of the isolates showed resistance to all of ampicillin, amoxicillin, and cephaloth...

AIM To determine the genetic basis and types of beta-lactamase encountered among enterobacterial isolates of wild pets from the animal exhibit. MATERIALS AND METHODS A total of 17 beta-lactamase-producing enterobacteria recovered from fecal samples of wild pet animals were analyzed for a selected beta-lactamase gene by polymerase chain reaction. RESULTS Molecular analysis identified one or ...