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Sleep is essential for physical and niental health. In the last 15 years there has grown up the concept of the brain stem reticular activating system. Electroencephalographic studies have shown two qualitatively different and alternat ing kinds of sleep, the orthodox (“slowwave―, or “¿ fore-brain―) and the paradoxical (“hind brain―, “¿ rapid eye movement―, “¿ activated―, or ...
The aggregation of the â-peptide into amyloid is a key pathological event in Alzheimer’s disease. This process (â-amyloidosis) involves the conversion of soluble random coil, R-helical or â-sheet conformations into insoluble, aggregated â-pleated sheet structures. The pH is a significant extrinsic factor that influences â-amyloidosis, which must be related to the presence of ionizable groups in...
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Aniline and o-, m-, and /Moluidine, which are representative of aro matic amines in cigarette smoke, were identified and quantified in human urine. Smokers excreted 3.1 ±2.6 «¿g/24 h of aniline and 6.3 ±3.7 ¿ig/ 24 h of o-toluidine (n = 16). Nonsmokers excreted 2.8 ±2.5 Mg/24 h of aniline and 4.1 ±3.2 un; 24 h of o-toluidine (n = 12). Metaand /»toluidine were detected in the urine of 2 ...
To determine the type of mutation induced by 8-hydroxyguanine in a mammalian system, we examined the mutations induced by a synthetic i -I la-ruv protooncogene containing 8-hydroxyguanine in the second po sition of codon 12 (GGC) in NIH3T3 cells. Transaction of this gene significantly increased the number of transformed foci. The c-Ha-r<w gene present in these foci was analyzed by the polymeras...
Data defining the isolated effect of insulin on whole body protein and glucose metabolism in cancer patients are limited. Ten normal volun teers (controls), age 55 ±3 years (mean ±SEM); 8 cancer patients, age 61 ±3years, weight loss 2 ±1% (CANWL); and 8 cancer patients, age 55 ±2 years, weight loss 18 ±2% (CAWL), were studied in the postabsorptive state. Whole body leucine kinetics were d...
APEC Study Centre, University of Auckland, Auckland, New Zealand    Abstract:  One of the key sets of questions underlying Asia Pacific economic cooperation over the last decade has been over the nature and form of the regional trade architecture that would gradually emerge from the turmoil of the Asia-Pacific ânoodle bowlâ of bilateral and plurilateral FTAs, and how that architecture...
Based on the recent literature of heterogeneous firms, productive firms self select themselves into foreign markets. In this framework, there is a productivity rise prior to exporting. On the other words, different export performance across firms is linked to their heterogeneity. Â The main purpose of the present paper is to examine the so-called hypothesis of heterogeneous firm in Iran. For ...
Institut de Recherches sur les Leucémies,Paris, France ¡M.W., C. J., M. B., Je. B.j; Acute Leukemia Group B Operations Office, Buffalo, New York 14203 [O. J. G., J. F. H./ ; State University of New York-Downstate Affiliated Hospitals, Brooklyn, New York 11238 [R. L./; The National Cancer Institute-Baltimore Cancer Research Center, Baltimore, Maryland, 21211 ¡A.A. S., P. H. W./; The Mount Sin...
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