BACKGROUND The salutogenic model has been established as a health promoting resource that is related to a strong sense of coherence (SOC), positive subjective health and quality of life (QoL). The aim of the study was to compare internal and external resources, life style factors, perceived health and QoL in Japan and Austria and to determine associations among these factors. METHODOLOGY AND ...

Abstract. Bellman, Kalaba, and Lockett recently proposed a numerical method for inverting the Laplace transform. The method consists in first reducing the infinite interval of integration to a finite one by a preliminary substitution of variables, and then employing an n-point Gauss-Legendre quadrature formula to reduce the inversion problem (approximately) to that of solving a system of n line...

Six novel keto carotenoids have been isolated from the stick insect. The structure of the pre­ dominant red pigment has been assigned to 3,4,3',4'-tetradehydro-/?,/?-carotene-2,2'-dione on the basis of electronic, infrared, and mass spectra. Minor pigments are 3,4-didehydro-/?,^-carotene-2,2'dione, 2'-hydroxy-3,4-didehydro-/?,/?-caroten-2-one, and 2'-hydroxy-/?,/?-caroten-2-one. Two other com­ ...

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U rsel S tuh lem m er, W ern er H aussm ann , F ran k M ilek , W olfgang K reis, and E rn s t R e in h a rd Pharmazeutisches Institut, Eberhard-Karls-Universität, A uf der Morgenstelle 8 D-72076 Tübingen, Bundesrepublik Deutschland Z. Naturforsch. 48 c, 713-721 (1993); received July 23,1993 Digitalis lanata, Biotransformation, Cardenolide Biosynthesis, Cell-Free System, 3 a-Hydroxysteroid-5 ß-o...

In the fetal lung, endogenous transforming growth factor-ß (TGF-ß) inhibits early morphogenesis and blocks hormone-induced type II cell differentiation. We hypothesized that endogenous TGF-ß inhibits type II cell differentiation and that the stimulatory effects of glucocorticoids result in part from suppression of TGF-ß. Epithelial cells were isolated from human fetal lung and cultured under de...

Further investigation of polar constituents in white lupin roots revealed the presence of genistein 7-O-ß-glucoside (la), genistein 4'-0-ß-glucoside (lb), 2'-hydroxygenistein 7-0ß-glucoside (2a) and 2'-hydroxygenistein 4'-0-ß-glucoside (2b) as simple isoflavone gluco­ sides; luteone 7-O-ß-glucoside (3 a), licoisoflavone A 7-O-ß-glucoside (4 a) and licoisoflavone A 4'-0-ß-glucoside (4b) as preny...

Abstract Introduction Sleep disorders constitute a major public health burden yet remain widely undiagnosed and untreated. The prevalence of diagnosed sleep associations with objectively measured sleep-wake dysfunction vary across populations. Here, we examined the self-reported objective architectural correlates four in large sample individuals using consumer technology. Methods Data from 33,4...

Two isomeric partially acetylated galactocerebrosides, ß-D-galactopyranosyl (2,3,4-tri-O-acetyl)and ß-Dgalactopyranosyl (2,4,6-tri-O-acetyl)-1’(3’-O-acetyl)ceramide, were prepared from galactocerebroside and sulfatide, respectively. Their galactofuranosylation produced ß-D-galactofuranosyl-6and ß-D-galactofuranosyl-3-ß-Dgalactopyranosyl-1’ceramide, as demonstrated by 1 H and 13 C NMR spectra as...

ß-catenin is a key component of the Wnt signaling pathway and the abnormal accumulation of ß-catenin is characteristic of various types of cancer. Here we demonstrate that overexpression of Sox4 enhances ß-catenin/TCF activity by increasing the stability of ß-catenin. Sox4 increased the protein level of ß-catenin and its target gene cyclin D1 in a dose-dependent manner. An siRNA experiment for ...