Streptococcus mutans, a dental pathogen, secretes different kinds of lantibiotic and nonlantibiotic bacteriocins. For self-protection, a bacteriocin producer strain must possess one or more cognate immunity mechanisms. We report here the identification of one such immunity complex in S. mutans strain GS-5 that confers protection against Smb, a two-component lantibiotic. The immunity complex tha...

A new approach of flow modulation comprehensive two-dimensional gas chromatography-mass spectrometry (GC x GC-MS) with supersonic molecular beam (SMB) and a quadrupole mass analyzer is presented. Flow modulation uniquely enables GC x GC-MS to be achieved even with the limited scan speed of quadrupole MS, and its 20 ml/min column flow rate is handled, splitless, by the SMB interface. Flow modula...

In the Maker-Breaker domination game played on a graph $G$, Dominator's goal is to select dominating set and Staller's claim closed neighborhood of some vertex. We study cases when Staller can win game. If Dominator (resp., Staller) starts game, then $\gamma_{\rm SMB}(G)$ SMB}'(G)$) denotes minimum number moves needs win. For every positive integer $k$, trees $T$ with SMB}'(T)=k$ are characteri...

Chromatographic separations are widespread in the fine chemicals and pharmaceutical industries for the downstream processing of complex mixtures with similar thermodynamic properties. In recent years, continuous chromatographic processes, in particular Simulated Moving Bed (SMB) processes are increasingly applied in industry. SMB processes are characterized by a counter-current movement of the ...

OBJECTIVE Little is known about the impact of diabetes self-management behavior (SMB) on long-term outcomes. We aimed to examine the association among patient-reported SMB, intermediate clinical outcomes, and mortality in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Data were collected from 340 patients with type 2 diabetes of the KORA-A study (1997/1998) who were recruited from...

Recently, Shao et al. proposed two bidirectional proxy re-signature schemes Smb and Sid−mb [3]. In their paper, the authors gave security proofs to say that both of them are secure in their security model without random oracles. But, we found that the scheme Smb is miss leaded and its security proof is false. In this paper, we present an attack on Smb and improve it to be secure in their securi...

It is very important to get financial supporting for Small and Medium Business(SMB) from the banks, which can set up a effective credit assessing system so that it can dispel misgiving of bank in the cause of the loaning to SMB. According to the credit grade assessment for SMB in practice and the related theories, a set of index system which assesses a SMB’s credit grade is established. Basing ...

We have performed a future projection of the climate and surface mass balance (SMB) of Svalbard with the MAR (Modèle Atmosphérique Régional) regional climate model forced by MIROC5 (Model for Interdisciplinary Research on Climate), following the RCP8.5 scenario at a spatial resolution of 10 km. MAR predicts a similar evolution of increasing surface melt everywhere in Svalbard followed by a sudd...

This paper presents a multi-level optimization strategy to obtain optimum operating conditions (four flowrates and cycle time) of nonlinear simulated moving bed chromatography. The multi-level optimization procedure (MLOP) approaches systematically from initialization to optimization with two objective functions (productivity and desorbent consumption), employing the standing wave analysis, the...

Whereas the sympathetic nervous system has a well-established role in blood pressure (BP) regulation, it is not clear whether long-term levels of BP are affected by parasympathetic function or dysfunction. We tested the hypothesis that chronic blockade of the parasympathetic nervous system has sustained effects on BP, heart rate (HR), and BP variability (BPV). Sprague-Dawley rats were instrumen...