Hepatic glucose metabolism is zonated. Glycolysis is mainly localized in hepatocytes surrounding the hepatic vein (pericentral zone) whereas gluconeogenesis is mainly carried out by hepatocytes surrounding the portal vein (periportal zone). Expression of the gene encoding the gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PEPCK, PCK1) is reduced upon feeding. PEPCK is considered a peri...

1 We investigated the factors producing zonation patterns of the dominant plants in south-eastern USA salt marshes where Juncus roemerianus dominates the high marsh, and Spartina alterniflora the middle and low marsh. 2 Juncus did not occur naturally in the Spartina zone and performed poorly when transplanted there, irrespective of whether neighbours were present or removed, indicating that its...

This project utilizes microfluidic systems to study how groups of liver cells acquire emergent tissue properties. Hepatocytes (the parenchymal cells of the liver) respond to many cues in their microenvironment: neighboring cells, growth factors, extracellular matrix, dissolved oxygen, and their interactions. One tissue property of interest is the compartmentalization of gene expression in multi...

Abstract: Aim Zooplankton functional groups play an important role in lake functioning and can readily respond to environmental changes may be associated with phytoplankton changes. In warmer regions, zooplankton species have a smaller body size, which decreases their grazing capacity, attenuating top-down control throughout phytoplankton. We evaluated density biomass of relationship algal hori...

Here, we present a novel method for culturing kidneys in low volumes of medium that offers more organotypic development compared to conventional methods. Organ culture is a powerful technique for studying renal development. It recapitulates many aspects of early development very well, but the established techniques have some disadvantages: in particular, they require relatively large volumes (1...

Land preservation and restoration are important tools for managing imperiled aquatic species, but they are often applied in the absence of a transparent scheme of geographic prioritization. To help guide preservation and restoration efforts in the Conasauga River Basin in Georgia and Tennessee, we used the “Zonation” algorithm to prioritize sub-watersheds. Zonation is a prioritization system th...

drought is a complex natural phenomenon that can occur in any climate. hydrologic drought in the river flow of arid and semi-arid areas causes serious shortages, threatens the quality of life, and impacts on the economy. understanding this feature is then essential for the management of water resources. hydrologic drought in the sense of deficient river flow is defined as the periods that river...