ACUTE LYMPHOBLASTIC leukemias (ALL) are characterized by clonal proliferation, accumulation, and tissue infiltration of neoplastic cells. They are mainly regarded as childhood diseases, with an early incidence peak at 2 to 5 years of age, where they represent about 80% of the childhood leukemias in the United States, and occur with an incidence of up to 30 cases per 1 million population per yea...

Replication studies on prometaphase chromosomes of man, the chimpanzee, the pygmy chimpanzee, the gorilla, and the orangutan reveal great interspeeifie homologies between the autosomes. The early replicating X chromosomes clearly show a high degree of conservation of both the pattern and the time course of replication. An early replicating segment on the short arm of the X chromosomes of man (X...

This paper focuses on the potential applications of regenerative medicine to include cell and biomaterialbased therapies for treating combat casualties at early echelons. The intent is to explore and evaluate the potential improvements, such as faster healing and/or greater functional outcome, that can be gained from applications of these medical technologies at the early echelons to include Le...