نتایج جستجو برای: yersinia pestis
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The Black Death is possibly the most infamous pandemic in human history, which killed onethird of the European population and subsequently shaped Western civilization (reviewed in [5]). Epidemics occurred in relentless cycles up to the seventeenth century, until severe depopulation caused a gradual decline in cases. All this was caused by a single pathological agent, the Gram-negative bacterium...
We have sequenced a region from the pgm locus of Yersinia pestis KIM6+ that confers sensitivity to the bacteriocin pesticin to certain strains of Escherichia coli and Y. pestis. The Y. pestis sequence is 98% identical to the pesticin receptor from Yersinia enterocolitica and is homologous to other TonB-dependent outer membrane proteins. Y. pestis strains with an in-frame deletion in the pestici...
Enteropathogenic yersiniae (Yersinia pseudotuberculosis and Yersinia enterocolitica) typically cause chronic disease as opposed to the closely related Yersinia pestis, the causative agent of bubonic plague. It is established that this difference reflects, in part, carriage by Y. pestis of a unique 9.6-kb pesticin or Pst plasmid (pPCP) encoding plasminogen activator (Pla) rather than distinction...
Plague, a highly infectious disease caused by Yersinia pestis, has killed millions of people in history and is still active the natural foci world nowadays. Understanding spatiotemporal patterns plague outbreaks critically important, as it may help facilitate prevention control for potential future outbreaks. This study's objective was to estimate effect topography, vegetation, climate, other e...
UNLABELLED Since its identification as the causative agent of plague in 1894, thousands of Yersinia pestis strains have been isolated and stored. Here, we report the ability of Y. pestis to survive up to 47 years in agar stabs, in rubber-stoppered tubes, under refrigeration (+4 to +10°C), although overall subculture recovery rates were poor and inversely related to the length of time stored. Ge...
Yersinia spp. are animal pathogens, some of which cause human disease. We sequenced 10 Yersinia isolates (from six species: Yersinia enterocolitica, Y. fredericksenii, Y. kristensenii, Y. pestis, Y. pseudotuberculosis, and Y. ruckeri) to high-quality draft or complete status. The genomes range in size from 3.77 to 4.94 Mbp.
A successful method has been developed for the detection of live Yersinia pestis, the plague bacillus, which incorporates nascent RNA synthesis. A fluorescent in situ hybridization (FISH) assay using peptide nucleic acid (PNA) probes was developed specifically to differentiate Y. pestis strains from closely related bacteria. PNA probes were chosen to target high copy mRNA of the Y. pestis caf1 ...
Yersinia pestis, the etiologic agent of plague, is closely related to Yersinia pseudotuberculosis evolutionarily but has a very different mode of infection. The RNA-binding regulatory protein, Hfq, mediates regulation by small RNAs (sRNAs) and is required for virulence of both Y. pestis and Y. pseudotuberculosis. Moreover, Hfq is required for growth of Y. pestis, but not Y. pseudotuberculosis, ...
doi:10.4102/ojvr.v81i2.722 http://www.ojvr.org Authors: B.M. Hang’ombe1 M. Ziwa2 M. Haule2 I. Nakamura3 K.L. Samui1 D. Kaile4 A.S. Mweene1 B.S. Kilonzo5 E.F. Lyamuya2 M. Matee2 C. Sugimoto3 H. Sawa3 B.W. Wren6 Affiliations: 1School of Veterinary Medicine, University of Zambia, Zambia 2Muhimbili University of Health and Allied Sciences, Tanzania 3Hokkaido University Research Center for Zoonosis ...
Genomics research provides an unprecedented opportunity for us to probe into the pathogenicity and evolution of the world's most deadly pathogenic bacterium, Yersinia pestis, in minute detail. In our present work, extensive microarray analysis in conjunction with PCR validation revealed that there are considerable genome dynamics, due to gene acquisition and loss, in natural populations of Y. p...
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