To intensify the brewing process and increase the fermenter productivity, many breweries throughout the world have been embracing high-gravity brewing. However, increasing original wort concentration can cause a negative effect on yeast fermentation performance. This study focused on the application of fed-batch fermentation in high-gravity brewing. High gravity worts of 24oBx (using 30% high m...

among the ways of pigment production, microbial synthesis has gained more interest for high growth rate, easy extraction and high yield. pigments are used in the food industry as natural colorants and preservatives; they also have pharmaceutical applications. in this study, fungus monascus purpureus ptcc 5303 was used to produce red, orange and yellow pigments. at first, significant variables w...

the effects of different sources of carbon, nitrogen and some of trace elements on cultivation of bacillus thuringiensis h14 were studied. glucose, glycerol, sodium acetate, (nh4)2so4, corn steep liquor, yeast extract, hydrolyzed casein, ca2+, mg2+ and mn2+ were the main parameters evaluated by plackett-burman statistical method. all elements have insignificant effect on germination while spore...

The Box-Wilson central composite design (CCD) based on response surface methodology (RSM) was used for ethanol fermentation using very high gravity (VHG) finger millet hydrolysate. Optimized process variables were namely, concentrations of yeast extract, magnesium sulphate and pH of the medium. High gravity mashes (>300 g dissolved solids per liter) were prepared by a thermo-stable α-amylase, f...

In this study, the feasibility of cruxrhodopsin (CR) production as a multifunctional nanoparticle was investigated and optimized by Halorculasp. IRU1, a novel halophile Archaea isolated from Urmia Lake, Iran in batch experiments. In this case, Taguchi method was used for effect measurement of three important factors (petrochemical wastewater, yeast extract and KH2PO4) on CR production. Results ...

The mechanisms involved in the food perception and selection remain poorly explored in many invertebrates including Drosophila melanogaster. Although our knowledge on these processes has rapidly increased, less is known about the mechanism of deciding or changing in the food preferences of Drosophila. This study explores how the type of media in Drosophila food affect male and female Drosophila...

In this study it was aimed to investigate inducibility of secondary metabolism in Astragalus chrysochlorus by yeast extract which is known to cause the synthesis of defensive phenolic metabolites. Cell suspension cultures of Astragalus chrysochlorus responded to elicitor treatment (10 gl(-1) yeast extract) by increasing phenylalanine ammonia lyase (PAL E.C. 4.3.1.5) activity the key enzyme of p...

In this work, the effects of medium composition and fermentation parameters on the simultaneous production of mycelial biomass and exopolymer by medicinal mushroom Hericium erinaceus CZ-2 were investigated in shake flask cultures using one-factor-at-a-time method and orthogonal array design. Results showed that the most suitable carbon, nitrogen, mineral sources, and cofactors for the mycelial ...

background: recombinant monoclonal antibodies have been marketed in last three decades as the major therapeutic proteins against different cancers. however choosing a proper medium and supplements to reach the high expression is a challenging step. despite of commercial serum free and chemically defined media, there are still numerous researches seeking the optimum media to gain higher expressi...

Cassia fistula seeds have many therapeutic uses in traditional medicine practice. The present investigation was undertaken to demonstrate the anticandidal activity of the C. fistula seed extract at ultra-structural level through transmission electron microscope (TEM) and scanning electron microscope (SEM) observations. The effect of seed extract on the growth profile of the Candida albicans was...