Abstract Background Tumour necrosis factor ligand superfamily member 8 (TNFL8) is a cytokine that plays vital roles in immune activations and inflammatory responses through its interaction with the tumour member. Despite multiple studies on involvement of receptor response, there limited information molecular characterization structural elucidation cytokine. Considering significance cytokine, t...

BACKGROUND Leishmania (Leishmania) aethiopica and L. (L.) tropica cause cutaneous leishmaniases and appear to be related. L. aethiopica is geographically restricted to Ethiopia and Kenya; L. tropica is widely dispersed from the Eastern Mediterranean, through the Middle East into eastern India and in north, east and south Africa. Their phylogenetic inter-relationship is only partially revealed. ...

BACKGROUND A common practice of managing pain globally is the combination of analgesics and this is aimed at facilitating patient compliance, simplifying prescription, and improving efficacy without increasing adverse effects. Fruit extracts of Xylopia aethiopica are used traditionally in the management of pain disorders and xylopic acid (XA) present in the fruit extract have been shown to poss...

Abstract Background The fruits of Xylopia aethiopica and seeds leaves Piper guineense are commonly used as spices. Due to their wide use in nutrition traditional medicine, there is need examine the biochemical histological effects ethanolic extracts on liver kidney function male albino rats . test animals (groups 2, 3 4) received 100 mg/kg each corresponding extract for 21 days. Group 1 served ...