نتایج جستجو برای: wpw syndrome
تعداد نتایج: 621956 فیلتر نتایج به سال:
he management of an asymptomatic child incidentally iscovered to have Wolff-Parkinson-White (WPW) synrome on electrocardiogram (ECG) is a controversial issue. ne big impediment to settling the controversy is our gnorance about the natural history of asymptomatic WPW yndrome. In this issue of the Journal, Santinelli et al. (1) eport the largest cohort (to date) of children with asympomatic WPW s...
The Wolff-Parkinson-White (WPW) syndrome was believed to be associated with PRKAG2 gene mutations. In this study, we verified the pathopoiesis of G100S mutation, a novel mutation only discovered in Chinese patients with WPW, in cardiac disorder. Similar to R302Q, when overexpressed PRKAG2 G100S mutant in zebrafish, we observed a thicker heart wall, detected a decreased AMPK enzymatic activity b...
We have mapped a disease locus for Wolff-Parkinson-White syndrome (WPW) and familial hypertrophic cardiomyopathy (FHC) segregating in a large kindred to chromosome 7 band q3. Although WPW syndrome and FHC have been observed in members of the same family in prior studies, the relationship between these two diseases has remained enigmatic. A large family with 25 surviving individuals who are affe...
Among patients with a Wolff–Parkinson–White (WPW) syndrome, approximately half will experience arrhythmia during their lifetime. Radiofrequency catheter ablation of the accessory atrioventricular pathway is the treatment of choice for this condition and is associated with a high success rate. Electrophysiology study is indeed the key procedure for identifying the target of radiofrequency ablati...
We have mapped a disease locus for Wolff-Parkinson-White syndrome (WPW) and familial hypertrophic cardiomyopathy (FHC) segregating in a large kindred to chromosome 7 band q3. Although WPW syndrome and FHC have been observed in members of the same family in prior studies, the relationship between these two diseases has remained enigmatic. A large family with 25 surviving individuals who are affe...
ECG changes during exercise stress testing, such as false-positive ST-segment depression and disappearance of the delta wave, are reported in patients with the Wolff-Parkinson-White (WPW) pattern. We present a case of exercise testing in a 53-year-old man with WPW syndrome with ischemic-appearing ECG changes and normal nuclear stress perfusion study findings who was thought to be at clinically ...
Mutations of AMPKγ2 subunit, N488I (AMPKγ2) and R531G (AMPKγ2), are associated with Wolff-Parkinson-White (WPW) syndrome, a cardiac disorder characterized by ventricular pre-excitation in humans. Cardiacspecific transgenic overexpression of human AMPKγ2 or AMPKγ2 leads to constitutive AMPK activation and the WPW phenotype in mice. However, overexpression of these mutant proteins also caused pro...
The atriofascicular accessory pathway (AP), known as the Mahaim pathway, is a rare form of pre-excitation, comprising less than 3% of all APs. Mahaim AP is characterized by decremental, anterograde-only conduction, and antidromic tachycardia with left bundle branch morphology. Prevalence of Mahaim AP in Ebstein's anomaly is significantly high. In addition, combination of Wolff-Parkinson-White (...
ASSOCIATION of cardiac murmurs with the Wolff-Parkinson-White (WPW) syndrome has been reported by several investigators .1 In the reported cases, however, the murmurs were not directly attributed to hemodynamic alterations produced by pre-excitation. This communication describes three patients with systolic murmurs related to pre-excitation. In one patient the murmur was heard only when the ele...
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