AbstractIn the present work we set out to investigate the neuroprotective effects of noscapine (0.5-2 µM) in presence of D-glucose on primary murine foetal cortical neurons after oxygen–glucose deprivation/24 hrs recovery. Cell viability, nitric oxide production and intracellular calcium ([ca2+]i) levels were evaluated by MTT assay, the modified Griess method and Fura-2 respectively. 25 and 100...

hyperdontia or supernumerary teeth in both arches without any syndromic manifestation are extremely rare. supernumerary teeth are commonly associated with gardner’s syndrome, cleft lip and palate, cleidocranial dysplasia and trichorhinophalangeal syndrome. five cases of non-syndromic multiple premolars of maxillary and mandibular arches in indian patients are presented here. this case series re...

background: the predominant phytoestrogen in soy and derived products is the isoflavone genistein. genistein has antioxidant properties. morphine is a main psychoactive chemical in opium that can increase the generation of free radicals and therefore it could adversely affects the spermatogenesis. objective: the main goal was to investigate whether the genistein could protect morphine adverse e...

limitations of water and nitrogen in soil usually restrict plant growth. the objective of this study was to evaluate the effects of different amounts of supplemental irrigation at different growth stages and application of different rates of nitrogen fertilizer on grain yield and water productivity of wheat cultivars. a field experiment was conducted in the agricultural research station of shah...

Rhododendron dauricum L. is an ancient Chinese traditional herb. The pharmacological effects of R. dauricum extract have been shown in chronic tracheitis. The aim of this study was to investigate the cardiovascular effects of Rhododendron dauricum L. flavonoids (RF) on rats and its mechanisms. This study was performed in isolated vascular rings and a rat model of myocardial infarction and isola...

Mitochondrial morphology is the result of balance between mitochondrial fusion and fission processes. mediated by cytosolic GTPase DRP1 which anchored to outer membrane (OMM) MiD49, MiD51, Mff. Changes in due alterations or proteins impact cytoplasmic ([Ca2+]cyt) ([Ca2+]mt) calcium homeostasis. Previous studies from our laboratory showed that cells a patient bearing MiD49 deleterious mutation e...

Supplemental Figures.......................................................................................................................2 Supplemental Figure 1. Schematic representation of the particle swarm optimization algorithm used for finding network parameters that produce the required responses in area MT....................................................................................