Merger and Acquisition fever continues. Whereas the M & A boom of the 1980s was driven largely by financial considerations, resulting in many leveraged buyouts and hostile takeovers, more of today’s mergers and acquisitions are friendly and are motivated by strategic profit goals. Reflecting this transition, marketing synergy has become a more relevant factor in determining the ultimate success...

We establish a new lower bound on the l-wise collective minimum degree which guarantees the existence of a perfect matching in a k-uniform hypergraph, where 1 ≤ l < k/2. For l = 1, this improves a long standing bound by Daykin and Häggkvist [4]. Our proof is a modification of the approach of Han, Person, and Schacht from [8]. In addition, we fill a gap left by the results solving a similar ques...

Two general classes of multiple decision functions, where each member of the first class strongly controls the family-wise error rate (FWER), while each member of the second class strongly controls the false discovery rate (FDR), are described. These classes offer the possibility that optimal multiple decision functions with respect to a pre-specified Type II error criterion, such as the missed...

In phase II platform trials, 'many-to-one' comparisons are performed when K experimental treatments are compared with a common control to identify the most promising treatment(s) to be selected for Phase III trials. However, when sample sizes are limited, such as when the disease of interest is rare, only a single Phase II/III trial addressing both treatment selection and confirmatory efficacy ...

Gene expression microarrays have been the vanguard of new analytic approaches in high-dimensional biology. Draft sequences of several genomes coupled with new technologies allow study of the influences and responses of entire genomes rather than isolated genes. This has opened a new realm of highly dimensional biology where questions involve multiplicity at unprecedented scales: thousands of ge...