• A great variety of mathematical and physical models of the human arterial system has been introduced, since the start of investigations in this field, with the dual purpose of gaining a better quantitative understanding of arterial performance and deriving clinical information in cases that deviate from normal." They can basically be divided in two groups: the "windkessel" models, the main ch...

The non-invasive quantification of arterial wave reflection is an increasingly important concept in cardiovascular research. It is commonly based on pulse wave analysis (PWA) of aortic pressure. Alternatively, wave separation analysis (WSA) considering both aortic pressure and flow waveforms can be applied. Necessary estimates of aortic flow can be measured by Doppler ultrasound or provided by ...

We present a new model of human cardiac electromechanics for the left ventricle where electrophysiology is described by Reaction–Eikonal and which enables an off-line resolution reaction model, thus entailing big saving computational time. Subcellular dynamics coupled with tissue mechanics, in turn Windkessel blood circulation. Our numerical results show that proposed able to provide physiologi...

The mechanism of the well-documented increase in aortic pulse pressure (PP) with age is disputed. Investigators assuming a classical windkessel model believe that increases in PP arise from decreases in total arterial compliance (C(tot)) and increases in total peripheral resistance (R(tot)) with age. Investigators assuming a more sophisticated pulse transmission model believe PP rises because i...

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In this work, we propose to use parametric models for the estimation of arterial tree input impedance. The results of this new method are compared with those of the standard method based on the Fast Fourier Transform (FFT). The comparison is first made with pressure and flow measurements on a calf, then with human blood pressure measurements completed by blood flow data simulated from a soliton...

Recent studies have demonstrated the benefits of using fractional derivatives to simulate a blood pressure profile. In this work we propose combine one-dimensional model coronary flow with fractional-order Windkessel boundary conditions. This allows us obtain greater variety profiles for better personalization An algorithm parameter identification is described, which used fit measured mean valu...