Typhoid is a global problem. Conventional diagnostic methods have limitations. The Widal test gives a high proportion of false positive results, and indiscriminate use of antibiotics has reduced the utility of blood culture. Consequently, these procedures are inadequate for diagnosing suspected cases of typhoid that do not present clear-cut symptoms. We previously showed that PCR-based diagnosi...

Background: To study the reliability of a single Widal test and to find out the diagnostic significance of ‘O’ and ‘H’ agglutinin titre in the diagnosis of typhoid fever. Methods: Community-based case-control study conducted from Jan 2001 to June 2007. The blood samples were collected from the medical and out door department of Sir Ganga Ram Hospitals, Lahore. The diagnostic value of an acute p...

The worldwide gold standard of diagnosing of enteric fever depends on the isolation of Salmonella enterica serovar Typhi from a patient's bone marrow and/or blood culture. In Libya clinicians are heavily dependent on the Widal test for diagnosis of enteric fever which has been used without determining the locally appropriate threshold titer, because the laboratories lack the skilled, experience...

The diagnostic value of the Widal test was assessed in an endemic area. The test was done on 300 normal individuals, 297 non-typhoidal fevers and 275 bacteriologically proven cases of typhoid. Of 300 normal individuals, 2% had an H agglutinin titre of 1/160 and 5% had an O agglutinin titre of 1/160. On the basis of these criteria a significant H and/or O agglutinin titre of 1/320 or more was ob...

Background and Objective: The diagnosis of typhoid fever in children is a challenge due to the non-specific clinical picture. The current role of the Widal test for diagnosis in developing countries has not been clear. Materials and Methods: Charts were reviewed on all children ≤ 15 years of age discharg...

Condition on admission.?Temperature, 102?F.; pulse rate, 112; respirations, 26 per minute. The pulse was of fairly good volume and did not give any indication of internal haemorrhage at the time. Tongue, coated and moist. Abdomen, slightly tympanitic, resonant all over, and not rigid. No enlargement of spleen and liver. Bowels constipated for about four days after the last two hemorrhagic stool...

PURPOSE To investigate the differences in clinical features and laboratory findings between group D and non-group D non-typhoidal Salmonella (NTS) gastroenteritis in children. METHODS A retrospective chart review of children diagnosed with NTS confirmed by culture study was performed. The clinical features and laboratory findings of group D and non-group D NTS were compared. RESULTS From 20...

Methods: This observational case series includes 14 patients with clinical features of CHIKV infection and associated optic neuritis. Complete ophthalmic evaluations were performed, as well as other examinations, including Mantoux test, Widal test, blood profile, color vision, neuroimaging, visual fields, visual evoked potentials, VDRL test, and enzyme-linked immunosorbent assay for CHIKV-speci...

Salmonella serotypes, including Typhi, S. Paratyphi A, B, and C, are responsible for the systemic, protracted febrile sickness known as typhoid fever. Various antibody-based tests being used diagnosing This study was carried out to assess performance of widal test blood culture diagnosis fever among malaria-negative patients in a tertiary care hospital east Delhi, India. The conducted from July...