The DREAM (DP, Retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell cycle genes, but its mechanism of action is poorly understood. Here we show that Caenorhabditis elegans DREAM targets have an unusual pattern of high gene body HTZ-1/H2A.Z. In mutants of lin-35, the sole p130/Rb-like gene in C. elegans, DREAM targets have reduced gene body HTZ-1/H2A.Z...

In this paper, we present Dream, a component-based software framework for the construction of resource-aware message-oriented middleware that can be assembled statically or dynamically. Dream is based on Fractal, a recent component model featuring hierarchical composition, component sharing and component binding. Dream allows building different forms of message-oriented middleware, from distrib...

BACKGROUND Previous studies have implicated the cyclic adenosine monophosphate/protein kinase A pathway as well as FosB and dynorphin-B expression mediated by dopamine D1 receptor stimulation in the development of 3,4-dihydroxyphenyl-L-alanine (L-DOPA)-induced dyskinesia. The magnitude of these molecular changes correlates with the intensity of dyskinesias. The calcium-binding protein downstrea...

Downstream regulatory element antagonist modulator (DREAM) is a Ca(2+)-binding protein that binds DNA and represses transcription in a Ca(2+)-dependent manner. Previous work has shown a role for DREAM in cerebellar function regulating the expression of the sodium/calcium exchanger 3 (NCX3) in cerebellar granular neurons to control Ca(2+) homeostasis and survival of these neurons. To achieve a g...

The purpose of the study was to examine the helpful components involved in the Hill’s cognitive-experiential dream work model. Participants were 27 volunteer clients from colleges and universities in northern and central parts of Taiwan. Each of the clients received 1–2 sessions of dream interpretations. The cognitive-experiential dream work model was applied to these clients by three therapist...

Tissue-specific gene expression depends on the interaction between tissue-specific and general transcription factors. DREAM is a Ca2+-dependent transcriptional repressor widely expressed in the brain where it participates in nociception through its control of prodynorphin gene expression. In the periphery, DREAM is highly expressed in the thyroid gland, the immune system, and the reproductive o...

This paper discusses how a qualitative understanding on the physics of failure can lead to a theoretical derivation of effective features that are useful for condition monitoring of wet friction clutches. The physical relationships between the features and the mean coefficient of friction (COF) which can be seen as the representation of the degradation level of a wet friction clutch are theoret...

studying persian heroic epic verses affected by narrative tradition and shahname is one of the areas that can be analyzed from  different perspectives. samname which is considered as the last national epic in persian literature and apparently is written in late 7th century and early 8th century – if we accept to be written by khajooye kermani- is among these works which is similar to shahname f...

BACKGROUND DREAM (Downstream Regulatory Element Antagonistic Modulator) is a neuronal calcium sensor that was suggested to modulate TSH receptor activity and whose overexpression provokes an enlargement of the thyroid gland in transgenic mice. The aim of this study was to investigate somatic mutations and DREAM gene expression in human multinodular goiter (MNG). MATERIAL AND METHODS DNA and RNA...

Dream narration has a lengthy history in the Western literary tradition, functioning as the earliest iteration of the frame story. Dream narratives can be found in the Bible, and in Greek and Latin classical literature, but perhaps reached a zenith during the Medieval period, when dream visions became a central narratological strategy in theological texts and secular romances alike. Deriving fr...