Africa presents the most complex genetic picture of any continent, with a time depth for mitochondrial DNA (mtDNA) lineages >100,000 years. The most recent widespread demographic shift within the continent was most probably the Bantu dispersals, which archaeological and linguistic evidence suggest originated in West Africa 3,000-4,000 years ago, spreading both east and south. Here, we have carr...

OBJECTIVE This study examined the effect of parity on blood pressure (BP) readings and BMI among rural West African Dogon women. DESIGN Correlational research design. SETTING Sangha, West Africa PARTICIPANTS 133 West African Dogon Women METHODS Demographic survey including age, number of children, history of hypertension, and village affiliation. BP readings were taken in accordance wit...

Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria. Correspondence: T. A. John, Department of Pharmacology, Lagos State University College of Medicine, PMB 21266, Ikeja, Lagos. Email: [email protected] Tel: 234 7028338910 Abbreviations: SMC, Smooth muscle cell; CHAH, Chronic high altitude hypoxia; alpha SMA, alpha Smooth muscle actin; eNOS, endo...

Deparments of Morbid Anatomy, College of Medicine, University of Lagos, P.M.B.12003, Surulere, Lagos, Nigeria Histopathology & Molecular Pathology, Leeds General Infirmary, Leeds, LS1 3EX, UK *Correspondence: Dr. Fatimah B. Abdulkareem, Dept of Morbid Anatomy, College of Medicine University of Lagos, P.M.B.12003, Surulere, Lagos, Nigeria E-mail: [email protected] Abbreviations: CD, cluster di...

BACKGROUND: Incidence of epilepsy in elderly patients is higher than in any other group. The diagnosis of epilepsy in old age is particularly challenging and is often overlooked or missed. Selection of appropriate antiepileptic drugs (AEDs) for this group of patient also requires more attention than younger patients. OBJECTIVE: To summarise the clinical presentation, aetiology, diagnosis, treat...

PURPOSE Significant association has recently been reported between pseudoexfoliation glaucoma (XFG) and two single-nucleotide polymorphisms (SNPs), rs3825942, and rs1048661, in the lysyl oxidase-like 1 gene (LOXL1). The purpose of this study was to investigate whether XFG-associated variants of LOXL1 play a significant role in primary open-angle glaucoma in the Caucasian, African-American, and ...

BACKGROUND: Women constitute over 60 percent of the HIVinfected population in sub-saharan Africa. Highly active antiretroviral therapy (HAART) has improved the life span of people living with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS). Advances in scientific knowledge and management of the HIV-positive pregnant woman have also led to reduction in the risk ...

Department of Surgery, College Of Medicine, University of Lagos (CMUL) / Lagos University Teaching Hospital (LUTH), Lagos, Nigeria. *Correspondence: D. C. Obalum, Department of Surgery, CMUL/LUTH, Lagos, Nigeria. E-mail: [email protected] Abbreviations: DVT, Deep Vein Thrombosis; LMWH, Low Molecular Weight Heparin; THRIFT, Thromboembolic Risk Factors; TED, Thromboembolic Deterrent ABSTRACT BACK...

Maternal lineages of West Eurasian and North African origin account for 11.5% of total mitochondrial ancestry in Puerto Rico. Historical sources suggest that this ancestry arrived mostly from European migrations that took place during the four centuries of the Spanish colonization of Puerto Rico. This study analyzed 101 mitochondrial control region sequences and diagnostic coding region variant...

Departments of Ear, Nose & Throat,Pathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria *Correspondence: Dr K R Iseh, Department of Ear Nose and Throat, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria E-mail: [email protected] Abbreviations: DNA, Deoxyrebonucleic acid; EBV, Ebstein Barr virus; NPC, Nasopharyngeal cancer; UICC, Union International Centre le Canc...