BACKGROUND We tested the hypothesis that the amount of weight lost after Roux-en-Y gastric bypass (RYGBP) correlates with plasma ghrelin levels. METHODS 36 morbidly obese patients were studied 3 years after RYGBP (6 men, 30 women) with mean initial BMI 51 kg/m2 and 8 healthy controls (2 men, 6 women) with mean BMI 25 kg/m2. Subjects consumed a light breakfast, and the first blood sample was d...

BACKGROUND Long-term results from randomized, controlled trials that compare medical therapy with surgical therapy in patients with type 2 diabetes are limited. METHODS We assessed outcomes 5 years after 150 patients who had type 2 diabetes and a body-mass index (BMI; the weight in kilograms divided by the square of the height in meters) of 27 to 43 were randomly assigned to receive intensive...

BACKGROUND Birth weight has been shown to be positively associated with adult obesity, but relatively few studies have examined the associations with growth in specific periods of early childhood. OBJECTIVE The objective was to assess the association of measures of growth between birth and 5 y of age with adult measures of adiposity. DESIGN We conducted a longitudinal study of young adults ...

BACKGROUND The role of dairy calcium intake and serum vitamin D concentrations in weight loss is controversial. OBJECTIVE The objective was to assess the association of dairy calcium intake and serum vitamin D with weight loss. DESIGN We analyzed data from participants in the 2-y Dietary Intervention Randomized Controlled Trial (DIRECT) [n = 322; mean body mass index (BMI; in kg/m²): 31; me...

objective  the aim of this study was to evaluate and compare the effects of na valproate and phenobarbital on changes in the weight of epileptic patients following treatment for their condition using the drugs mentioned. materials and methods sixty epileptics were assigned into two groups of 30 patients each, the case and controls. the diagnosis was made on the basis of the international league...

Breast-feeding has been suggested to be associated with lower risks of obesity in older children and adults. We assessed whether the duration and exclusiveness of breast-feeding are associated with early postnatal growth rates and the risks of overweight and obesity in preschool children. The present study was embedded in a population-based prospective cohort study from early fetal life onwards...

BACKGROUND Whether the association between body mass index (BMI) and all-cause mortality for older adults is the same as for younger adults is unclear. OBJECTIVE The objective was to determine the association between BMI and all-cause mortality risk in adults ≥65 y of age. DESIGN A 2-stage random-effects meta-analysis was performed of studies published from 1990 to 2013 that reported the RR...

Background: Metabolically obese normal-weight (MONW) children and adolescents are characterized by body mass index (BMI) lower than +1SD with metabolic disorders such as hyperglycemia, hypertriglyceridemia, and/or hypertension. This study wants to determineprevalence of MONW, metabolically benign normal weight (MBNW), metabolically abnormality obese (MAO) and comparethe components of metabolic ...