OBJECTIVE To evaluate perceived patient burden and acceptability of whole body MRI (WB-MRI) compared to standard staging investigations, and identify predictors of reduced tolerance. METHODS Patients recruited to multicentre trials comparing WB-MRI with standard staging scans for lung and colorectal cancer were invited to complete two questionnaires: a baseline questionnaire at recruitment, m...

BACKGROUND Diagnosis based on prion detection in lymph nodes of sheep and goats can improve active surveillance for scrapie and, if it were circulating, for bovine spongiform encephalopathy (BSE). With sizes that allow repetitive testing and a location that is easily accessible at slaughter, retropharyngeal lymph nodes (RLN) are considered suitable organs for testing. Western blotting (WB) of b...

BACKGROUND Sarcopenic obesity (SO) is characterized by a combination of low muscle and high fat mass with an additive negative effect of both conditions on cardiometabolic risk. The aim of the study was to determine the effect of whole-body electromyostimulation (WB-EMS) on the metabolic syndrome (MetS) in community-dwelling women aged ≥70 years with SO. METHODS The study was conducted in an ...

BACKGROUND Whole blood (WB) has been used in combat since World War I as it is readily available and replaces every element of shed blood. Component therapy has become standard; however, recent military successes with WB resuscitation have revived the debate regarding wider WB use. Characterization of optimal WB storage is needed. We hypothesized that refrigeration preserves WB function and tha...

Obesity is a global epidemic associated with a higher risk of cardiovascular disease and metabolic disorders, such as type 2 diabetes. Previous studies demonstrated that chronic feeding of steamed wheat bran (WB) decreases obesity. To clarify the underlying mechanism and the responsible component for the anti-obesity effects of steamed WB, we investigated the effects of dietary steamed WB and a...

BACKGROUND Gap junctional intercellular communication decreases with HSV-2 infection. To determine the importance of functional gap junctions for infectivity, we compared HSV-2 growth in communication-competent and -deficient cell lines. METHODS HSV-2 infectivity was tested in five cell lines: WB rat liver epithelial cells (communication-competent), WB-aB1 (communication-deficient), WB-a/32-1...

The pervasiveness of explicit and implicit weight bias (WB) defined as negative stereotypes and prejudice regarding one's weight has been observed among individuals of all weight categories. As a source of WB, health messages have been discussed due to reinforcing stigmatizing notions. The present study sought to investigate whether health messages (i.e., eat healthy, become physically active) ...

PURPOSE The purpose of this study was to examine the feasibility of a fast protocol for whole-body diffusion-weighted imaging (WB-DWI) using a slice-accelerated echo-planar sequence, which, when using comparable image acquisition parameters, noticeably reduces measurement time compared to a conventional WB-DWI protocol. MATERIALS AND METHODS A single-shot echo-planar imaging sequence capable ...

Proof of Lemma 1. Consider a low-performance bidder with unit valuation v who bids b and a high-performance bidder with unit valuation wv who bids wb. Both bidders get a score wb, and their payoff functions are U (y L , v, b) = y L (v − b)Pr(wb is the highest score) (W1) and U (y H , wv, wb) = y H (wv − wb)Pr(wb is the highest score). (W2) It is easy to establish that U (y H , wv, wb) = wy H y ...

The recommended algorithm for detection and characterization of serum human T-cell lymphotropic virus (HTLV) antibodies calls for first performing a screening enzyme immunoassay (EIA) and then further evaluating repeatedly reactive samples for antibodies recognizing specific HTLV glycoproteins (2, 3). A commercially available Western blot (WB) that includes both native and recombinant HTLV prot...