Myocardial remodeling is a major contributor in the development of heart failure (HF) after myocardial infarction (MI). Integrin-linked kinase (ILK), LIM-only adaptor PINCH-1, and α-parvin are essential components of focal adhesions (FAs), which are highly expressed in the heart. ILK binds tightly to PINCH-1 and α-parvin, which regulates FA assembly and promotes cell survival via the activation...

temperature restrictions on aqueous effluents dictate that streams with a temperature higher than the permitted level needed to pass through cooling systems to reduce the effluent temperature before discharge. in this study, by considering the grouping design rules based on pinch technology, an optimum design for a distributed effluent cooling system, has been developed. a counter-flow wet cool...

this study aimed to find an appropriate way to minimize water utility in the petrochemical and petroleum industries. for this purpose, tehran oil refinery was chosen to analyze feasibilities of regeneration, reuse and recycling in the water network. in this research, two key contaminants including cod and hardness were analyzed. amount of freshwater was reduced about 180 m3/h (53%) and 216.88 m...

It is shown how the pinch technique algorithm may be consistently extended beyond the one-loop level to obtain the gauge-independent two-loop fermion self-energy −iΣ̂(p) in QCD in the pinch technique approach. The starting point for the construction is the general diagrammatic representation of the two-loop quark self-energy in terms of renormalized one-loop twoand three-point function and tree ...

By using a water transmission line, current wave shaping was demonstrated for a fast capillary Z-pinch discharge recombination soft x-ray laser study. The pulsed power system consists of a water capacitor, a gap switch, a transmission line, and a capillary plasma load. A voltage wave initiated at the water capacitor propagates toward the capillary load through the transmission line. Control of ...

OBJECTIVE This study extended previous work of Rice, Leonard, and Carter [AJOT, 52(8), 621-626] and examined the relationship between grip and pinch strengths and the forces produced while accessing common household containers in healthy, elderly persons. METHOD Forty-two women and 9 men 60 years of age and older were assigned randomly to one of four order groups in a counterbalanced, repeate...

Many on-chip approaches that use flow-focusing to pinch the continuous aqueous phase into droplets have become the most popular methods that provide monodisperse emulsion droplets. However, not every lab can easily adapt a microfluidic workflow into their familiar protocols. We develop an off-chip approach, spinning micro-pipette liquid emulsion (SiMPLE) generator, to produce highly stable mono...

Pinch-outs refers to the gradual thinning of thickness sedimentary layer laterally until there is no deposition and are a major topic modern research on automated drawing geological profiles. The rapid development smart systems imposed an urgent need for high-speed, accurate methods plot pinch-outs. However, because their complexity, excessive number branch paths, low rendering speed, poor reli...

PINCH, integrin-linked kinase (ILK) and Ras suppressor-1 (RSU-1) are molecular scaffolding proteins that form a physical complex downstream of integrins, and have overlapping roles in cellular adhesion. In Drosophila, PINCH and ILK colocalize in cells and have indistinguishable functions in maintaining wing adhesion and integrin to actin linkage in the muscle. We sought to determine whether the...