In this study, toxicological safety (mutagenicity) and therapeutic potential (antimutagenicity) of water extract of Centella asiatica Linn., were evaluated using the Allium cepa assay. The mitotic index (MI) at 6.25% concentration of the extract decreased significantly from 3.13% to 2.05% after 24 h and 48 h, respectively, however, the MI increased significantly by 60% and 400% at 12.5% and 50....

A sequential solvent extraction scheme was employed for the extraction of antioxidant compounds from kenaf (Hibiscus cannabinus L.) seeds. Yield of extracts varied widely among the solvents and was the highest for hexane extract (16.6% based on dry weight basis), while water extract exhibited the highest total phenolic content (18.78 mg GAE/g extract), total flavonoid content (2.49 mg RE/g ext...

The leaf and stem of cordia macleodii plant were investigated for evaluating antibacterial and antifungal properties. Different extracts of leaf and stem viz. double distilled water, methanol, ethyl acetate ane n-hexane were collected and content was optimized for the maximum amount of extraction with varying time of 6 and 12 h. The extracts were tested for their antimicrobial activities agains...

background and objectives: recently, use of herbal medicine and plant extracts as a substitute for commercially available chemical drugs for control of infectious diseases such as dental caries and periodontal disease has become increasingly popular. the present study was aimed to evaluate the effect of rhus coriaria l. water extract on five common oral bacteria and bacterial biofilm formation ...

sporadic alzheimer’s disease (sad) is affected by genetic risk factors, aging and oxidative stresses. the herbal extract of r. canina, t. vulgare and u. dioica has a beneficial role in aging, as an anti-inflammatory and anti-oxidative agent. we investigate the neuroprotective effects of this herbal extract in the rat model of sad.  the rats were divided into control, sham, model, herbal extract...

Compared to studies of water extracts of plants, those utilising alkaline extracts are limited. Both water and alkaline extracts from licorice root were compared regarding their biological activities. Licorice root was successively extracted first with water or alkaline solution (pH 9 or 12), and the alkaline (pH 12.0) extract was further separated into 50% ethanol-soluble and -insoluble fracti...

The antigen preparation most often used for determining the levels of antibodies to virulence-associated proteins of Shigella spp. consists of a mixture of proteins (including IpaB, IpaC, IpaD, and VirG*) extracted from virulent shigellae with water (water extract). To overcome the lack of specificity for individual antigens in the water-extract enzyme-linked immunosorbent assay (ELISA), the ip...

Parkinson's disease (PD) is a chronic neurodegenerative disorder having close relationship with oxidative stress induced by reactive oxygen species (ROS). Cortex Fraxini (QP) is a kind of traditional Chinese medicinal herb with antioxidant properties. It may be a potential candidate for preventing the development of chronic neurodegenerative diseases. Thus, the key objective of the current stud...

The present study evaluated the antimutagenic and anticancer activities of A. marina leaf extract. The antimutagenic activity of ethanol and water extracts of A. marina leaf (concentration 10 mg/plate for 48 h) was evaluated using the Salmonella typhimurium TA100 strain in the Ames test with (+S9) and without (−S9) metabolic activation, and its anticancer effect with concentrations of 200, 400,...

the water extract of trigonella foenum graecum stem and leaves was tested for lethal activity against hymenolepis nana, syphacia obvelata, and moniezia expansa. the plant extract demonstrated good anthelmintic activity in vitro which is directly related to the concentration of the extract used. the extract also prevents the formation of ascaris larvae from the eggs of ascaris lumbrico- ides (hu...